Fusidic acid

Fusidic acid structural formula

CAS Number6990-06-3
Molecular FormulaC31H48O6
Molecular Weight516.719
InChI KeyIECPWNUMDGFDKC-MZJAQBGESA-N
LogP5.22
Synonyms
  • Fusidic acid
  • (3alpha,4alpha,5alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17Z)-16-(Acetyloxy)-3,11-dihydroxy-4,8,14-trimethyl-18-norcholesta-17,24-dien-21-oic acid
  • 5-Heptenoic acid, 2-[(3alpha,4alpha,5alpha,8alpha,9beta,11alpha,13alpha,14beta,16beta,17Z)-16-(acetyloxy)-3,11-dihydroxy-4,8,10,14-tetramethylgonan-17-ylidene]-6-methyl-, (2Z)-
  • 6990-06-3
  • 29-Nordammara-17(20),24-dien-21-oic acid, 16-(acetyloxy)-3,11-dihydroxy-, (3?,4?,8?,9?,11?,13?,14?,16?,17Z)-
  • 29-Nor-8?,9?,13?,14?-dammara-17(20),24-dien-21-oic acid, 3?,11?,16?-trihydroxy-, 16-acetate, (Z)-
  • acide fusidique
  • acido fusidico
  • Flucidin
  • Fucithalmic
  • Fusidinic acid
  • Fusidinsaure
  • NSC 56192
  • Ramycin
  • C.A.S. 62,602; Diethanolamine fusidate
  • EINECS 230-256-0
  • Fucidin acid
  • Acidum fusidicum
  • UNII-59XE10C19C
  • Fusidine
  • fucidic acid

Applications:

Separation of Fusidic acid on Newcrom R1 HPLC column

February 16, 2018
Separation of Fusidic acid on Newcrom C18 HPLC column

Fusidic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Fusidic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.