Ellagic acid

Ellagic acid structural formula

CAS Number476-66-4
Molecular FormulaC14H6O8
Molecular Weight302.195
InChI KeyAFSDNFLWKVMVRB-UHFFFAOYSA-N
LogP0.146
Synonyms
  • Ellagic acid
  • 2,3,7,8-Tetrahydroxy[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione
  • [1]Benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione, 2,3,7,8-tetrahydroxy-
  • 476-66-4
  • 5-19-07-00108
  • [1]Benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione, 2,3,7,8-tetrahydroxy-
  • [1,1'-Biphenyl]-2,2'-dicarboxylic acid, 4,4',5,5',6,6'-hexahydroxy-, di-?-lactone
  • acide ellagique
  • acido elagico
  • Alizarin yellow
  • Alizarine Yellow
  • Benzoaric acid
  • Elagostasine
  • Eleagic acid
  • Ellagsaure
  • Gallogen
  • Lagistase
  • BRN 0047549
  • Diphenic acid, 4,4',5,5',6,6'-hexahydroxy-, di-delta-lactone
  • EINECS 207-508-3
  • NSC 407286
  • 2,3,7,8-Tetrahydroxy(1)benzopyrano(5,4,3-cde)(1)benzopyran-5,10-dione
  • NSC 656272
  • Acidum ellagicum
  • UNII-19YRN3ZS9P
  • Pomegranate juice
  • 2,3,7,8-tetrahydroxy[1]benzopyrano[5,4,3-cde][1]benzopyran-5,10-dione
  • 4,4',5,5',6,6'-hexahydroxydiphenic acid 2,6,2',6'-dilactone
  • 6,7,13,14-tetrahydroxy-2,9-dioxatetracyclo[6.6.2.04,16.011,15]hexadeca-1(15),4,6,8(16),11,13-hexaene-3,10-dione
  • Benzoarate
  • Eleagate
  • Ellagate
  • Ellagic acid dihydrate
  • Ellagic acid hydrate
  • Ellagsaeure
  • Gallogen
  • Llagate
  • Llagic acid

Applications:

HPLC Method For Analysis of Ellagic Acid on Newcrom BH Column

September 13, 2021

Separation type: Liquid Chromatography Mixed-mode


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High Performance Liquid Chromatography (HPLC) Method for Analysis of Ellagic Acid

Ellagic acid (EA) is a naturally occurring polyphenol. The best sources of ellagic acid in the diet are pomegranate, strawberries, raspberries, blackberries, and walnuts. It has been investigated extensively because of its antiproliferative action in some cancers, along with its anti-inflammatory effects. Ellagic acid can be retained on HPLC mixed-mode Newcrom BH column using a mobile phase consisting of methanol (MeOH) and water with perchloric acid (HClO4) buffer. The analysis method can be UV detected at 253 nm.

 

Condition
Column Newcrom BH, 2.1×100 mm, 5 µm, 100A
Mobile Phase MeOH/H2O – 40/60%
Buffer HClO4 – 0.5%
Flow Rate 0.2 ml/min
Detection UV 253  nm

Description
Class of Compounds Acid
Analyzing Compounds Ellagic Acid

 

Application Column

Newcrom BH

Column Diameter: 2.1 mm
Column Length: 100 mm
Particle Size: 5 µm
Pore Size: 100 A

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Application Analytes:
Ellagic acid
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of Ellagic acid on Newcrom R1 HPLC column

February 16, 2018
Separation of Ellagic acid on Newcrom C18 HPLC column

Ellagic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Ellagic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.