Diethyl (cyanomethyl)phosphonate

Diethyl (cyanomethyl)phosphonate structural formula

CAS Number2537-48-6
Molecular FormulaC6H12NO3P
Molecular Weight177.140
  • Diethyl (cyanomethyl)phosphonate
  • Phosphonic acid, P-(cyanomethyl)-, diethyl ester
  • 2537-48-6
  • Phosphonic acid, (cyanomethyl)-, diethyl ester
  • (cianometil)fosfonato de dietilo
  • (Cyanomethyl)diethoxyphosphine oxide
  • (cyanomethyl)phosphonate de diethyle
  • (Cyanomethyl)phosphonic acid diethyl ester
  • (Diethoxyphosphinyl)acetonitrile
  • (Diethoxyphosphono)acetonitrile
  • (Diethylphosphono)acetonitrile
  • 2-(Diethylphosphonyl)acetonitrile
  • Cyanomethanephosphonic acid, diethyl ester
  • Diethyl cyanomethanephosphonate
  • Diethyl-(cyanomethyl)phosphonat
  • NSC 407826
  • O,O-Diethyl (cyanomethyl)phosphonate
  • Phosphonic acid, P-(cyanomethyl)-, diethyl ester
  • EINECS 219-806-0


Separation of Diethyl (cyanomethyl)phosphonate on Newcrom R1 HPLC column

Separation of Diethyl (cyanomethyl)phosphonate on Newcrom R1 HPLC column

Diethyl (cyanomethyl)phosphonate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail:" or by phone: 847-229-2629.

Application Analytes:
Diethyl (cyanomethyl)phosphonate