Di-tert-butyl dicarbonate

Di-tert-butyl dicarbonate structural formula

CAS Number24424-99-5
Molecular FormulaC10H18O5
Molecular Weight218.249
InChI KeyDYHSDKLCOJIUFX-UHFFFAOYSA-N
LogP2.40
Synonyms
  • Di-tert-butyl dicarbonate
  • Carbonic acid, (1,1-dimethylethoxy)carbonyl 1,1-dimethylethyl ester
  • 24424-99-5
  • Dicarbonic acid, bis(1,1-dimethylethyl) ester
  • Bis(1,1-dimethylethyl) dicarbonate
  • Bis(tert-butyl) dicarbonate
  • BOC-anhydride
  • Carbonate de di(tert-butyle)
  • carbonato de di(terc-butilo)
  • di(tert-butyl) carbonate
  • Di(tert-butyl)carbonat
  • Dicarbonic acid bis(1,1-dimethylethyl)ester
  • Dicarbonic acid, C,C'-bis(1,1-dimethylethyl) ester
  • DI-T-BUTYL DICARBONATE
  • Di-tert-butyl oxydiformate
  • Di-tert-butyl pyrocarbonate
  • Formic acid, oxydi-, di-tert-butyl ester
  • Pyrocarbonic acid di-tert-butyl ester
  • tert-Butoxycarbonyl anhydride
  • tert-Butyl dicarbonate
  • EINECS 246-240-1
  • UNII-Z10Q236C3G
  • Boc2O
  • bis(tert-butoxycarbonyl)oxide

Applications:

Separation of Di-tert-butyl dicarbonate on Newcrom R1 HPLC column

February 16, 2018
Separation of Di-tert-butyl dicarbonate on Newcrom C18 HPLC column

Di-tert-butyl dicarbonate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Di-tert-butyl dicarbonate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.