| CAS Number | 50-36-2 |
|---|---|
| Molecular Formula | C17H21NO4 |
| Molecular Weight | 303.358 |
| InChI Key | ZPUCINDJVBIVPJ-PFSRBDOWSA-N |
| LogP | 2.30 |
| Synonyms |
|
Applications:
HPLC Method for Analysis of Cocaine
April 29, 2016
Cocaine, also known as coke, is mostly used as a recreational drug. It is a strong stimulant. The drug’s most common appearance in powder form is a salt, usually cocaine hydrochloride. Due to Cocaine rapidly metabolizing in the body, so if it’s ingested/inhaled, its concentration in urine usually does not exceed 10% that of its principal metabolite, benzoylecgonine. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Cocaine. The method is UV compatible and can be used as a general approach for analyzing similar compounds.
| Column | Primesep 200, 3.2×100 mm, 5 µm, 100A |
| Mobile Phase | Gradient MeCN – 5-50% |
| Buffer | Gradient H3PO4 – 0.05-0.3%, 5 min, 4 min hold |
| Flow Rate | 0.5 ml/min |
| Detection | UV, 270 nm |
| Class of Compounds |
Drug, Acid, Hydrophilic, Ionizable, |
| Analyzing Compounds | Cocaine |
Application Column
Primesep 200
The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.
Select options
