Benzenesulfonyl fluoride, 4-methyl-

Benzenesulfonyl fluoride, 4-methyl- structural formula

CAS Number455-16-3
Molecular FormulaC7H7FO2S
Molecular Weight174.191
  • Benzenesulfonyl fluoride, 4-methyl-
  • 4-Methylbenzene-1-sulfonyl fluoride
  • 455-16-3
  • 4-11-00-00375
  • BRN 2208423
  • EINECS 207-238-6
  • p-Methylbenzenesulfonyl fluoride
  • p-Methylphenylsulfonyl fluoride
  • NSC 2749
  • Toluene-4-sulfonyl fluoride
  • Toluene-p-sulphonyl fluoride
  • 4-Tolylsulfonyl fluoride
  • Tosyl fluoride


Separation of Benzenesulfonyl fluoride, 4-methyl- on Newcrom R1 HPLC column

February 16, 2018
Separation of Benzenesulfonyl fluoride, 4-methyl- on Newcrom C18 HPLC column

Benzenesulfonyl fluoride, 4-methyl- can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Benzenesulfonyl fluoride, 4-methyl-
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: or by phone: 847-229-2629.