Dibazol (Bendazol)

Bendazol [INN:DCF] structural formula

CAS Number621-72-7
Molecular FormulaC14H12N2
Molecular Weight208.265
InChI KeyYTLQFZVCLXFFRK-UHFFFAOYSA-N
LogP3.23
Synonyms
  • Bendazol [INN:DCF]
  • 2-Benzyl-1H-benzimidazole
  • 1H-Benzimidazole, 2-(phenylmethyl)-
  • 621-72-7
  • 5-23-08-00498
  • 2-Benzylbenziminazole
  • BRN 0159495
  • Dibasol
  • Dibazol
  • Dibazole
  • EINECS 210-703-6
  • NSC 60020
  • 2-(Phenylmethyl)-1H-benzimidazole
  • Tromasedan
  • Bendazolo
  • Bendazolum
  • UNII-26601THN1D

Applications:

Separation of Dibazol (Bendazol) and Papaverine in Papazol Tablets on Newcrom BH Column

October 21, 2020


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Condition
Column Newcom BH, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 15/85%
Buffer HClO4 – 0.3%
Flow Rate 1.0 ml/min
Detection UV 265 nm

Description
Class of Compounds Drug
Analyzing Compounds Dibazol (Bendazol),  Papaverine

 

Application Column

Newcrom BH

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Dibazol (Bendazol)
Papaverine
Papaverine hydrochloride
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of Bendazol [INN:DCF] on Newcrom R1 HPLC column

May 16, 2018
Separation of Bendazol [INN:DCF] on Newcrom R1 HPLC column

Bendazol [INN:DCF] can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Dibazol (Bendazol)
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.