all-trans-Retinoic acid

all-trans-Retinoic acid structural formula

CAS Number302-79-4
Molecular FormulaC20H28O2
Molecular Weight300.442
InChI KeySHGAZHPCJJPHSC-YCNIQYBTSA-N
LogP6.30
Synonyms
  • all-trans-Retinoic acid
  • Retinoic acid
  • 302-79-4
  • ATRA
  • Tretinoin
  • all-trans-Vitamin A acid
  • Atragen
  • Aberel
  • (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
  • Retinoic acid
  • (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexene-1-yl)-2,4,6,8-nonatetraenoic acid
  • 2,4,6,8-Nonatetraenoic acid, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-
  • 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoic acid
  • Acide retinoique
  • Aknoten
  • all-(E)-Retinoic acid
  • all-trans-Tretinoin
  • all-trans-?-Retinoic acid
  • Cordes Vas
  • Dermairol
  • Epi-Aberel
  • NSC 122578
  • NSC 122758
  • Retacnyl
  • Retin A
  • Retinoic acid, all-trans-
  • trans-Retinoic acid
  • Tretin M
  • Tretin M, 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-, (all-E)-
  • tretinoine
  • tretinoino
  • Vesanoid
  • Vesnaroid
  • Vitamin A acid
  • Vitamin A acid, all-trans-
  • Vitamin A1 acid, all-trans-
  • ?-Retinoic acid
  • Acid A Vit (Belgium, Netherlands)
  • A-Acido
  • Aknefug
  • Alltrans-retinoic acid
  • all-trans-Vitamin A1 acid
  • 15-Apo-beta-caroten-15-oic acid
  • BRN 2057223
  • 3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-all-trans-tetraenoic acid
  • Effederm
  • EINECS 206-129-0
  • NSC-122758
  • beta-RA
  • Retin-A
  • Vitamin a acid, trans-
  • Atralin
  • Retin-A Micro
  • Aberela
  • Acnavit
  • A-Vitaminsyre
  • Avitoin
  • Tretinoina
  • Tretinoinum
  • Betarretin
  • UNII-5688UTC01R
  • Refissa
  • all-trans Retinoic acid
  • (2E,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-tetraenoic acid
  • (all-E)-3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoate
  • 3,7-Dimethyl-9-(2,6,6-trimethyl-1-cyclohexen-1-yl)-2,4,6,8-nonatetraenoate
  • Acide retinoique (French)
  • All-(E)-Retinoate
  • Retinoate
  • Tretinoine (French)
  • beta-Retinoate
  • trans-Retinoate
  • 187175-63-9
  • 56573-65-0
  • 7005-78-9

Applications:

Separation of all-trans-Retinoic acid on Newcrom R1 HPLC column

February 19, 2018
Separation of all-trans-Retinoic acid on Newcrom C18 HPLC column

all-trans-Retinoic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
all-trans-Retinoic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.