| CAS Number | 115-77-5 |
|---|---|
| Molecular Formula | C5H12O4 |
| Molecular Weight | 136.147 |
| InChI Key | WXZMFSXDPGVJKK-UHFFFAOYSA-N |
| LogP | -1.69 |
| Synonyms |
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Applications:
Uv-Vis Spectrum of Pentaerythritol
January 26, 2026
If you are looking for optimized HPLC method to analyze Pentaerythritol check our HPLC Applications library
For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The spectra presented here are measured with an acidic mobile phase that has a pH of 3 or lower.
HPLC Separation of Maleic Acid and Pentaerythritol
July 10, 2012

Application Notes: Maleic acid is a small hydrophilic acid, which is poorly retained in reversed-phase chromatography. Pentaerythritol is hydrophilic neutral molecule. A miixed-mode HILIC/anion-exchange method was developed on Obelisc N HPLC column. The retention time for maleic acid can be controlled by amount of ACN, buffer pH, and buffer concentration. Pentaerythritol retention time is only controlled by the amount of acetonitrile. The method is LC/MS and ELSD compatible.
Application Columns: Obelisc N
Application compounds: Maleic Acid, Pentaerythritol
Detection technique: LC/MS, ELSD/CAD
| Column | Obelisc N, 3.2×150 mm, 5 µm, 100A |
| Mobile Phase | MeCN/H2O – 95/5% |
| Buffer | AmFm pH 3.0- 5 mM |
| Flow Rate | 0.5 ml/min |
| Detection | ELSD |
| Class of Compounds |
Acid, Hydrophilic, Ionizable |
| Analyzing Compounds | Maleic Acid, Pentaerythritol |
Application Column
Obelisc N
SIELC has developed the Obelisc™ columns, which are mixed-mode and utilize Liquid Separation Cell technology (LiSC™). These cost-effective columns are the first of their kind to be commercially available and can replace multiple HPLC columns, including reversed-phase (RP), AQ-type reversed-phase, polar-embedded group RP columns, normal-phase, cation-exchange, anion-exchange, ion-exclusion, and HILIC (Hydrophilic Interaction Liquid Chromatography) columns. By controlling just three orthogonal method parameters - buffer concentration, buffer pH, and organic modifier concentration - users can adjust the column properties with pinpoint precision to separate complex mixtures.
Select optionsPentaerythritol
UV Detection

