4,4’-Diphenylmethane diisocyanate

4,4’-Diphenylmethane diisocyanate structural formula

CAS Number101-68-8
Molecular FormulaC15H10N2O2
Molecular Weight250.257
InChI KeyUPMLOUAZCHDJJD-UHFFFAOYSA-N
LogP4.05
Synonyms
  • 4,4'-Diphenylmethane diisocyanate
  • 1,1'-Methylenebis(4-isocyanatobenzene)
  • Benzene, 1,1'-methylenebis[4-isocyanato-
  • 101-68-8
  • 4,4'-Methylenedi(phenyl isocyanate)
  • 1,1'-Methylenebis [4-isocyanatobenzene]
  • 4,4'-MDI
  • 4-13-00-00396
  • Benzene, 1,1'-methylenebis[4-isocyanato-
  • 1,1'-Methylenebis[4-isocyanatobenzene]
  • 4,4'-Bis(isocyanatophenyl)methane
  • 4,4'-Diisocyanatodiphenylmethane
  • 4,4-DIPHENYLMETHANE DIISOCYANATE
  • 4,4'-Methylendiphenyldiisocyanat
  • 4,4'-Methylenebis(isocyanatobenzene)
  • 4,4'-Methylenebis(phenyl isocyanate)
  • 4,4'-methylenediphenyl diisocyanate
  • 4,4'-Methylenediphenyldiisocyanate
  • 4,4'-Methylenediphenylene isocyanate
  • 4,4'-Methylenedi-p-phenylene diisocyanate
  • Benzene-, 1,1'-methylenebis[4-isocyanato-
  • Benzene, 1,1'-methylenebis[4-isocyanto-
  • Bis(1,4-isocyanatophenyl)methane
  • BIS(4-ISOCYANATOPHENYL)METHANE
  • BIS(PHENYLISOCYANATE), 4,4'-METHYLENE-
  • Bis(p-isocyanatophenyl)methane
  • BIS[1-ISOCYANATOBENZENE], 4,4'-METHYLENE-
  • Di(4-isocyanatophenyl)methane
  • diisocianato de 4,4'-metilendifenilo
  • diisocyanate de 4,4'-methylenediphenyle
  • Diphenyl methane diisocyanate
  • DIPHENYL METHANEDIISOCYANATE
  • DIPHENYLMETHAN-4,4'-DIISOCYANAT
  • Diphenylmethane 4,4'-diisocyanate
  • Diphenylmethane 4,4-diisocyanate
  • Diphenylmethane-4.4'-diisocyanate
  • DIPHENYLMETHYL DIISOCYANATE
  • Diphenylmethylene diisocyanate
  • Isocyanic acid, diphenylmethylene ester
  • Isocyanic acid, methylenedi-p-phenylene ester
  • METHYLENE BISPHENYL ISOCYANATE
  • Methylene diphenyl diisocyanate
  • Methylenebis(4-isocyanatobenzene)
  • Methylenebis(4-phenyl isocyanate)
  • Methylenebis(4-phenylene isocyanate)
  • Methylenebis(phenylisocyanate)
  • Methylenebis(p-phenyl isocyanate)
  • Methylenebis(p-phenylene isocyanate)
  • Methylenebisphenylene diisocyanate
  • Methylenebisphenylene diisocyanate, 4,4'-
  • Methylenebis-p-phenylene diisocyanate
  • METHYLENE-DIPHENYLENE DI-ISOCYANATE (M.D.I.)
  • Methylenedi-p-phenylene diisocyanate
  • Methylenedi-p-phenylene isocyanate
  • Monomeric 4,4'-methylenediphenyl diisocyanate aerosol
  • NSC 9596
  • p,p'-Diphenylmethane diisocyanate
  • P,P'-METHYLENEBIS(PHENYL ISOCYANATE)
  • Phenylmethane diisocyanate
  • UN 2489
  • BRN 0797662
  • Desmodur 44
  • Di-(4-isocyanatophenyl)methane
  • 4,4'-Diphenylmethanediisocyante
  • EINECS 202-966-0
  • Isocyanic acid, ester with diphenylmethane
  • Isonate
  • Isonate 125M
  • Isonate 125 MF
  • Nacconate 300
  • NCI-C50668
  • para,para'-Methylenebis(phenyl isocyanate)
  • Rubinate 44
  • Difenil-metan-diisocianato
  • Difenylmethaan-dissocyanaat
  • UNII-B0LO6BBS8C
  • 1,1'-Methylenebis(4-isocyanatobenzene)
  • 4,4'-Methylenedi-p-phenylene diisocyanate
  • 4,4'-Methylenediphenyl isocyanate
  • 4,4'-Methylenediphenylene diisocyanate
  • 4,4'-methylene diphenyl diisocyanate
  • 4-4'-Diisocyanate de diphenylmethane
  • Bis(para-isocyanatophenyl)methane
  • Diphenyl methane diisocyanate
  • Diphenylmethane diisocyanate
  • Diphenylmethane-4,4'-diisocyanate
  • MDI
  • MDR
  • Methylbisphenyl isocyanate
  • Methylene bisphenyl isocyanate
  • Methylene di-p-phenylene isocyanate
  • Methylenebis(p-phenyl isocyanate)
  • Methylenebis(para-phenyl isocyanate)
  • Methylenebis(para-phenylene isocyanate)
  • Methylenebisphenyl diisocyanate
  • Methylenedi-p-phenylene diisocyanate
  • Methylenedi-para-phenylene diisocyanate
  • para,para'-Diphenylmethane diisocyanate
  • para,para'-Methylenebis(phenyl isocyanate)
  • 10031-75-1
  • 1211266-59-9
  • 1211316-64-1
  • 1220313-65-4
  • 1400594-70-8
  • 142690-07-1
  • 153986-89-1
  • 201528-77-0
  • 53633-14-0
  • 55157-41-0
  • 57460-66-9
  • 77090-48-3
  • 88001-94-9
  • 97568-33-7
  • 1533423-48-1
  • 1588489-56-8
  • 2031250-39-0
  • 2056146-02-0

Applications:

Separation of 4,4’-Diphenylmethane diisocyanate on Newcrom R1 HPLC column

February 19, 2018
Separation of 4,4’-Diphenylmethane diisocyanate on Newcrom C18 HPLC column

4,4’-Diphenylmethane diisocyanate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
4,4’-Diphenylmethane diisocyanate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.