4-Dodecylphenol

4-Dodecylphenol structural formula

CAS Number104-43-8
Molecular FormulaC18H30O
Molecular Weight262.438
InChI KeyKJWMCPYEODZESQ-UHFFFAOYSA-N
LogP7.91
Synonyms
  • 4-Dodecylphenol
  • Phenol, 4-dodecyl-
  • 104-43-8
  • Phenol, 4-?dodecyl-
  • Phenol, p-dodecyl-
  • p-Dodecylphenol
  • p-n-Dodecylphenol
  • p-dodecilfenol
  • EINECS 203-202-9
  • UNII-EZF5Y6P2G8

Applications:

HPLC Method for Separation of 2-Dodecylphenol and 4-Dodecylphenol on Chromni Column

September 23, 2026

HPLC Method for Analysis of 2-Dodecylphenol, 4-Dodecylphenol on Chromni Column by SIELC Technologies

High Performance Liquid Chromatography (HPLC) Method for Analysis of 2-Dodecylphenol, 4-Dodecylphenol.

Dodecylphenol is an alkylphenol chemical compound with the formula C18H30O. It is used primarily in industrial manufacturing of detergents, lubricants, and fuels. It is used as an intermediate in the mining industry as well as in the production of a wide variety of resins.

2-Dodecylphenol, 4-Dodecylphenol can be retained and analyzed using the Chromni stationary phase column. The analysis utilizes a gradient method with a simple mobile phase consisting of water and acetonitrile (MeCN). Detection is performed using UV.

Condition

ColumnChromni, 4.6 x 150 mm, 3 µm, 100 A, dual ended
Mobile PhaseMeCN
BufferNone
Flow Rate1.0 ml/min
DetectionUV 220 nm
LOD*1. 34.5 ppb, 2. 35.2 ppb
*LOD was determined for this combination of instrument, method, and analyte, and it can vary from one laboratory to another even when the same general type of analysis is being performed.

Description

Class of CompoundsPhenol
Analyzing Compounds2-Dodecylphenol, 4-Dodecylphenol

Application Column

Chromni

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 3 µm
Pore Size: 100 A
Column options: dual ended

Add to cart
Application Analytes:
2-Dodecylphenol
4-Dodecylphenol
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of 4-Dodecylphenol on Newcrom R1 HPLC column

February 16, 2018
Separation of 4-Dodecylphenol on Newcrom C18 HPLC column

4-Dodecylphenol can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
4-Dodecylphenol
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us before ordering the column as there may be a more suitable column alternative by either e-mail: support@sielc.com or by phone: 847-229-2629.