2,2-Dimethylpropanoic acid

2,2-Dimethylpropanoic acid structural formula

CAS Number75-98-9
Molecular FormulaC5H10O2
Molecular Weight102.134
InChI KeyIUGYQRQAERSCNH-UHFFFAOYSA-N
LogP1.48
Synonyms
  • 2,2-Dimethylpropanoic acid
  • Propanoic acid, 2,2-dimethyl-
  • 75-98-9
  • Pivalic acid
  • 4-02-00-00908
  • Propanoic acid, 2,2-dimethyl-
  • 2,2,2-Trimethylacetic acid
  • 2,2-Dimethyl propanoic acid
  • 2,2-Dimethylpropionic acid
  • ACETIC ACID, TRIMETHYL-
  • Acide pivalique
  • acido pivalico
  • Neopentanoic acid
  • Neovaleric acid
  • NSC 65449
  • PIVALINSAEURE
  • Pivalinsaure
  • tert-Pentanoic acid
  • Trimethylacetic acid
  • Trimethylmethanecarboxylic acid
  • Versatic 5 acid
  • ?,?-Dimethylpropionic acid
  • BRN 0969480
  • alpha,alpha-Dimethylpropionic acid
  • EINECS 200-922-5
  • Propionic acid, 2,2-dimethyl-
  • Kyselina 2,2-dimethylpropionova
  • Kyselina pivalova
  • UNII-813RE8BX41
  • acide 2,2-dimethylpropanoique

Applications:

Separation of 2,2-Dimethylpropanoic acid on Newcrom R1 HPLC column

May 16, 2018
Separation of 2,2-Dimethylpropanoic acid on Newcrom R1 HPLC column

2,2-Dimethylpropanoic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
2,2-Dimethylpropanoic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.