2-Chloroacrylic acid

2-Chloroacrylic acid structural formula

CAS Number598-79-8
Molecular FormulaC3H3ClO2
Molecular Weight106.511
InChI KeySZTBMYHIYNGYIA-UHFFFAOYSA-N
LogP0.695
Synonyms
  • 2-Chloroacrylic acid
  • 2-Chloroprop-2-enoic acid
  • 2-Propenoic acid, 2-chloro-
  • 598-79-8
  • BRN 1098503
  • EINECS 209-953-9
  • NSC 97174
  • 2-chloro-2-propenoic acid
  • alpha-chloroacrylic acid

Applications:

Separation of 2-Chloroacrylic acid on Newcrom R1 HPLC column

February 16, 2018
Separation of 2-Chloroacrylic acid on Newcrom C18 HPLC column

2-Chloroacrylic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
2-Chloroacrylic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us before ordering the column as there may be a more suitable column alternative by either e-mail: support@sielc.com or by phone: 847-229-2629.