2-Amino-5-methylbenzenesulfonic acid

2-Amino-5-methylbenzenesulfonic acid structural formula

CAS Number88-44-8
Molecular FormulaC7H9NO3S
Molecular Weight187.211
InChI KeyLTPSRQRIPCVMKQ-UHFFFAOYSA-N
LogP-0.987
Synonyms
  • 2-Amino-5-methylbenzenesulfonic acid
  • 2-Amino-5-methylbenzene-1-sulfonic acid
  • Benzenesulfonic acid, 2-amino-5-methyl-
  • 88-44-8
  • 3-14-00-02213
  • 4-Aminotoluene-3-sulfonic acid
  • 6-Amino-m-toluenesulfonic acid
  • 6-Amino-m-toluenesulfonic acid (SO3H=1)
  • 6-Amino-meta-toluenesulfonic acid (SO3H=1)
  • BRN 2211509
  • EINECS 201-831-3
  • NSC 7544
  • Ptmsptmsa
  • Red 4B acid
  • Kyselina 4-toluidin-3-sulfonova

Applications:

Separation of 2-Amino-5-methylbenzenesulfonic acid on Newcrom R1 HPLC column

February 19, 2018
Separation of 2-Amino-5-methylbenzenesulfonic acid on Newcrom C18 HPLC column

2-Amino-5-methylbenzenesulfonic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
2-Amino-5-methylbenzenesulfonic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.