| CAS Number | 23364-44-5 |
|---|---|
| Molecular Formula | C14H15NO |
| Molecular Weight | 213.27 |
| InChI Key | GEJJWYZZKKKSEV-KGLIPLIRSA-N |
| LogP | 1.3 |
| Synonyms |
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Applications:
HPLC Chiral Separation of 2-amino-1,2-diphenylethanol Enantiomers on Cyralis AM Column
August 4, 2026
HPLC Chiral Method for Analysis of (1S,2R)-(+)-2-Amino-1,2-diphenylethanol Enantiomers on Cyralis AM Column by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of (1S,2R)-(+)-2-Amino-1,2-diphenylethanol.
2-amino-1,2-diphenylethanol is a chiral organic chemical compound with the chemical formula C14H15NO. It is used primarily in asymmetric synthesis as a chiral auxiliary or ligand for enantioselective reactions. You can find detailed UV spectra of (1S,2R)-(+)-2-Amino-1,2-diphenylethanol and information about its various lambda maxima by visiting the following link.
This application describes a normal-phase chiral HPLC method for the separation of (1S,2R)-(+)-2-Amino-1,2-diphenylethanol enantiomers using SIELC’s Cyralis AM chiral column. Cyralis AM is an amylose-based chiral stationary phase (CSP) designed for enantiomeric separations, optical purity testing, chiral impurity analysis, and stereoisomer characterization in pharmaceutical, chemical, agrochemical, and fine chemical applications.
(1S,2R)-(+)-2-Amino-1,2-diphenylethanol can be retained and analyzed using the Cyralis AM stationary phase column. The analysis utilizes an isocratic method with a mobile phase consisting of Hexane, Ethanol, and Ethanolamine. Detection is performed using UV.
Condition
| Column | Cyralis AM, 4.6 x 100 mm, 5 µm, 100 A, normal phase |
| Mobile Phase | Hexane/Ethanol/Ethanolamine |
| Flow Rate | 1.0 mL/min |
| Detection | UV 230 nm |
| Resolution | 5.33 |
Description
| Class of Compounds | Compound |
| Analyzing Compounds | (1S,2R)-(+)-2-Amino-1,2-diphenylethanol |
Application Column
Cyralis AM
Column Diameter: 4.6 mm
Column Length: 100 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: normal phase
Uv-Vis Spectrum of (1S,2R)-(+)-2-Amino-1,2-diphenylethanol
February 25, 2026
Access the UV-Vis Spectrum SIELC Library
If you are looking for optimized HPLC method to analyze (1S,2R)-(+)-2-Amino-1,2-diphenylethanol check our HPLC Applications library
For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The spectra presented here are measured with an acidic mobile phase that has a pH of 3 or lower.
