| CAS Number | 1076-97-7 |
|---|---|
| Molecular Formula | C8H12O4 |
| Molecular Weight | 172.180 |
| InChI Key | PXGZQGDTEZPERC-UHFFFAOYSA-N |
| LogP | 0.814 |
| Synonyms |
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Applications:
HPLC Separation of cis- and trans – 1,4 cyclohexanedicarboxylic Acid on Newcrom BH Column
May 21, 2020
| Column | Newcrom BH, 4.6×150 mm, 5 µm, 100A |
| Mobile Phase | MeCN/H2O – 10/90% |
| Buffer | H2SO4 – 0.1% |
| Flow Rate | 1.0 ml/min |
| Detection | UV 200nm |
| Class of Compounds | Acid |
| Analyzing Compounds | cis- 1,4 cyclohexanedicarboxylic acid, trans – 1,4 cyclohexanedicarboxylic acid |
Application Column
Newcrom BH
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
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Separation of 1,4-Cyclohexanedicarboxylic acid on Newcrom R1 HPLC column
February 16, 2018
1,4-Cyclohexanedicarboxylic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select options