| CAS Number | 22065-85-6 |
|---|---|
| Molecular Formula | C13H17NO |
| Molecular Weight | 203.286 |
| InChI Key | SGIBOXBBPQRZDM-UHFFFAOYSA-N |
| LogP | 2.15 |
| Synonyms |
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Applications:
Uv-Vis Spectrum of 1-Benzylpiperidine-4-carbaldehyde
May 26, 2026
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If you are looking for optimized HPLC method to analyze 1-Benzylpiperidine-4-carbaldehyde check our HPLC Applications library
UV/Vis.: λmax: 190, 206, 262 nm
For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The compound was dissolved in acetonitrile. This analysis was done with the mobile phase made of acetonitrile.
HPLC Method for Separation of 1-Benzylpiperidine-4-carbaldehyde on Primesep 100 Column
May 26, 2026
HPLC Method for 1-Benzylpiperidine-4-carbaldehyde on Primesep 100 by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of 1-Benzylpiperidine-4-carbaldehyde
1-Benzylpiperidine-4-carbaldehyde is an organic chemical with the chemical formula
C13H17NO. It is primarily used in pharmaceutical and medicinal chemistry research as a building block and as a key intermediate in the synthesis of Donepezil. Its reactive aldehyde group and piperidine ring make it useful for synthesizing biologically active compounds. You can find detailed UV spectra of 1-Benzylpiperidine-4-carbaldehyde and information about its various lambda maxima by visiting the following link.
1-Benzylpiperidine-4-carbaldehyde can be retained and analyzed using the Primesep 100 stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of acetonitrile (MeCN). Detection is performed using UV.
| Column | Primesep 100, 4.6 x 150 mm, 5 µm, 100 A, dual ended |
| Mobile Phase | MeCN/H2O – 70/30% |
| Buffer | Sulfuric Acid – 0.1% |
| Flow Rate | 1.0 ml/min |
| Detection | UV 208 nm |
| Limit of Detection* | 34 ppb |
| Class of Compounds | Organic |
| Analyzing Compounds | 1-Benzylpiperidine-4-carbaldehyde |
Application Column
Primesep 100
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended
HPLC Method for Separation of Donepezil and 1-Benzylpiperidine-4-carbaldehyde on Primesep 100 Column
May 19, 2026
HPLC Method for Donepezil, 1-Benzylpiperidine-4-carbaldehyde on Primesep 100 by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Donepezil, 1-Benzylpiperidine-4-carbaldehyde
Donepezil is a medication with the chemical formula C24H29NO3. It is primarily used to treat dementia and improve cognition, but has not shown to cause any change in the progression of the disease. Some research suggests that it can be used to treat Lewy body dementia, effects of traumatic brain injury, and vascular dementia. 1-Benzylpiperidine-4-carbaldehyde is an important intermediate used in pharmaceutical and medicinal chemistry research. Its reactive aldehyde group and piperidine ring make it useful for synthesizing biologically active compounds.
You can find detailed UV spectra of Donepezil, 1-Benzylpiperidine-4-carbaldehyde and information about its various lambda maxima by visiting the following link.
Donepezil, 1-Benzylpiperidine-4-carbaldehyde can be retained and analyzed using the Primesep 100 stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of acetonitrile (MeCN). Detection is performed using UV.
| Column | Primesep 100, 4.6 x 150 mm, 5 µm, 100 A, dual ended |
| Mobile Phase | MeCN/H2O – 60/40% |
| Buffer | Sulfuric Acid – 0.2% |
| Flow Rate | 1.0 ml/min |
| Detection | UV 208 nm |
| Limit of Detection* | 1. 16 ppb, 2.0 18 ppb |
| Class of Compounds | Drug |
| Analyzing Compounds | Donepezil, 1-Benzylpiperidine-4-carbaldehyde |
Application Column
Primesep 100
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended
Donepezil
Separation of 1-Benzylpiperidine-4-carbaldehyde on Newcrom R1 HPLC column
May 16, 2018
1-Benzylpiperidine-4-carbaldehyde can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
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