Triazole acetic acid

Triazole acetic

CAS Number28711-29-7
Molecular FormulaC4H5N3O2
Molecular Weight127.1
InChI KeyRXDBSQXFIWBJSR-UHFFFAOYSA-N
LogP-0.3
Synonyms
  • 1,2,4-Triazole-1-acetic acid
  • 2-(1H-1,2,4-Triazol-1-yl)acetic acid
  • 1H-1,2,4-Triazole-1-acetic acid
  • [1,2,4]Triazol-1-yl-acetic acid
  • UNII-W3ASK2WBNH
  • 1H-1,2,4-triazol-1-ylacetic acid
  • 2-(1,2,4-triazol-1-yl)acetic acid
  • W3ASK2WBNH
  • (1H-1,2,4-Triazol-1-yl)acetic acid
  • 1H-1,2,4-Triazole-1-aceticacid
  • (1,2,4-triazol-1-yl)acetic acid
  • MFCD00036051
  • 2-(1,2,4-triazolyl)acetic acid
  • 1,2,4-triazol-1-ylacetic acid
  • EC-000.1972
  • 1,2,4 triazole acetic-acid
  • SCHEMBL1280420
  • 1,2,4-triazol-1-acetic acid
  • CTK1A7598
  • KS-00002AIV
  • DTXSID90365231
  • RXDBSQXFIWBJSR-UHFFFAOYSA-N
  • ZINC2168219
  • 1,2,4-triazole-1-acetic acid hcl
  • SBB010156
  • AKOS000118706
  • MCULE-7489588316
  • PS-5884
  • AC-11863
  • AB0040897
  • AB1007734
  • DB-019365
  • TR-012610
  • TR-044593
  • BB 0237751
  • CS-0072938
  • FT-0691052
  • ST50248023
  • Y8565
  • EN300-06654
  • K-7087
  • J-505330
  • Q27292248
  • Z56931716
  • F3230-0024

Applications:

HPLC Separation of Triazole acetic acid and 1,2,4-Triazole on Primesep 100 Column

December 13, 2019

HPLC Method for 1,2,4-Triazole, Triazole acetic acid on Primesep 100 by SIELC Technologies

High Performance Liquid Chromatography (HPLC) Method for Analysis of 1,2,4-Triazole, Triazole acetic acid

Triazole is a five-membered heterocyclic chemical ring containing three nitrogen atoms and two carbon atoms. It’s molecular formula is C₂H₃N₃. It is most commonly used as an antifungal drug. It works through inhibiting an enzyme in fungal cell wall synthesis.

1,2,4-Triazole, Triazole acetic acid can be retained and analyzed using the Primesep 100 stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with a Trifluoroacetic acid buffer. Detection is performed using CAD.

ColumnPrimesep 100, 4.6 x 150 mm, 5 µm, 100 A, dual ended
Mobile PhaseMeCN/H2O – 25/75%
BufferTFA – 0.1%
Flow Rate1.0 ml/min
DetectionCAD (Corona) MS- compatible mobile phase
Class of Compounds
Heterocyclic, Hydrophilic, Base
Analyzing Compounds1,2,4-Triazole, Triazole acetic acid

Application Column

Primesep 100

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
1,2,4-Triazole
Triazole acetic acid
Application Detection:
CAD Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.