p-Toluenesulfonyl chloride

p-Toluenesulfonyl chloride structural formula

CAS Number98-59-9
Molecular FormulaC7H7ClO2S
Molecular Weight190.640
InChI KeyYYROPELSRYBVMQ-UHFFFAOYSA-N
LogP2.24
Synonyms
  • p-Toluenesulfonyl chloride
  • 4-Methylbenzene-1-sulfonyl chloride
  • Benzenesulfonyl chloride, 4-methyl-
  • 98-59-9
  • 4-Methylbenzenesulfonyl chloride
  • Tosyl chloride
  • Benzenesulfonyl chloride, 4-methyl-
  • 4-Methylbenzene-1-sulfonyl chloride
  • 4-Methylphenylsulfonyl chloride
  • 4-Toluenesulfonyl chloride
  • 4-Toluensulfonyl chloride
  • 4-Toluolsulfonyl chloride
  • 4-Tosyl chloride
  • Chlorure de tosyle
  • cloruro de tosilo
  • NSC 175822
  • p-Methylbenzenesulfonyl chloride
  • p-Methylphenylsulfonyl chloride
  • p-Toluenesulfochloride
  • p-Toluenesulfonic acid chloride
  • p-Toluenesulfonic chloride
  • p-Toluenesulphonyl chloride
  • P-TOLUOLSULFONYLCHLORID
  • p-Tolylsulfonyl chloride
  • p-Tosyl chloride
  • TOLUENE-4-SULFONYL CHLORIDE
  • Toluenesulfonyl chloride
  • Tosylchlorid
  • EINECS 202-684-8
  • para-Toluenesulfochloride
  • para-Toluenesulfonyl chloride
  • 4-Toluenesulfonic acid, chloride
  • UNII-027KYN78B4

Applications:

Separation of p-Toluenesulfonyl chloride on Newcrom R1 HPLC column

February 16, 2018
Separation of p-Toluenesulfonyl chloride on Newcrom C18 HPLC column

p-Toluenesulfonyl chloride can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
p-Toluenesulfonyl chloride
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.