O,O-Diethyl chlorothiophosphate

O,O-Diethyl chlorothiophosphate structural formula

CAS Number2524-04-1
Molecular FormulaC4H10ClO2PS
Molecular Weight188.611
  • O,O-Diethyl chlorothiophosphate
  • O,O-Diethyl phosphorochloridothioate
  • Phosphorochloridothioic acid, O,O-diethyl ester
  • 2524-04-1
  • Phosphorochloridothioic acid, O,O-diethyl ester
  • 4-01-00-01352
  • BRN 0471434
  • Diethoxythiophosphoryl chloride
  • O,O-Diethyl chloridophosphorothioate
  • O,O-Diethyl chloridothionophosphate
  • O,O-Diethyl chlorothionophosphate
  • Diethyl chlorothiophosphate
  • Diethyl phosphorochloridothioate
  • Diethyl phosphorochloridothionate
  • Diethyl phosphorochlorothioate
  • O,O-Diethyl phosphorochlorothioate
  • Diethyl phosphorothiochloridate
  • O,O-Diethyl phosphorothiochloridate
  • Diethyl phosphorothionochloridate
  • O,O-Diethyl phosphorothionochloridate
  • O,O-Diethyl thionophosphoric acid ester chloride
  • O,O-Diethyl thionophosphoric chloride
  • O,O-Diethyl thionophosphorochloridate
  • O,O-Diethyl thionophosphoryl chloride
  • Diethyl thiophosphoric chloride
  • Diethyl thiophosphoryl chloride
  • O,O-Diethyl thiophosphoryl chloride
  • Diethylchlorothiophosphate
  • O,O-Diethylphosphorochloridothioate
  • Diethylthiophosphoric acid chloride
  • O,O-Diethylthiophosphorochloridate
  • EINECS 219-755-4
  • Ethyl PCT
  • NSC 43776
  • Phosphonothioic acid, chloro-, O,O-diethyl ester
  • Diethylchlorthiofosfat
  • O,O-Diethylester kyseliny chlorthiofosforecne
  • UNII-A310QMF5Q0
  • 1081841-50-0


Separation of O,O-Diethyl chlorothiophosphate on Newcrom R1 HPLC column

February 16, 2018
Separation of O,O-Diethyl chlorothiophosphate on Newcrom C18 HPLC column

O,O-Diethyl chlorothiophosphate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
O,O-Diethyl chlorothiophosphate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.