Norethindrone acetate

Norethindrone acetate structural formula

CAS Number51-98-9
Molecular FormulaC22H28O3
Molecular Weight340.464
InChI KeyIMONTRJLAWHYGT-ZCPXKWAGSA-N
LogP3.73
Synonyms
  • Norethindrone acetate
  • (17alpha)-3-Oxo-19-norpregn-4-en-20-yn-17-yl acetate
  • Estr-4-en-3-one, 17-(acetyloxy)-17-ethynyl-, (17beta)-
  • 51-98-9
  • 19-Norpregn-4-en-20-yn-3-one, 17-(acetyloxy)-, (17?)-
  • 17-Acetoxy-19-nor-17?-pregn-4-en-20-yn-3-one
  • 17-Hydroxy-19-nor-17?-pregn-4-en-20-yn-3-one acetate
  • 17?-Ethinyl-19-nortestosterone 17?-acetate
  • 17?-Ethinyl-19-nortestosterone acetate
  • 17?-Ethinyl-4-estrene-17?-ol-acetate-3-one
  • 17?-Ethynyl-19-nortestosterone acetate
  • 17?-Acetoxy-17?-ethinyl-4-estren-3-one
  • 17?-Acetoxy-19-nor-17?-pregn-4-en-20-yn-3-one
  • 17?-Hydroxy-19-nor-17?-pregn-4-en-20-yn-3-one acetate
  • 19-Nor-17?-pregn-4-en-20-yn-3-one, 17-hydroxy-, acetate
  • 19-Norethisterone acetate
  • 19-Norethynyltestosterone acetate
  • acetate de norethisterone
  • acetato de noretisterona
  • Aygestin
  • Estalis
  • Gynophase
  • Gynovlane
  • Milli-Anovlar
  • Milligynon
  • Miniphase
  • Norethindrone 17-acetate
  • Norethisteron acetate
  • Norethisteronacetat
  • Norethisterone 17-acetate
  • norethisterone acetate
  • Norethynyltestosterone acetate
  • Norethysterone acetate
  • Norlutate
  • Norlutin A
  • Norlutin acetate
  • NSC 22844
  • Orlutate
  • Primolut-Nor
  • Progylut
  • 17beta-Acetoxy-19-nor-17alpha-pregn-4-en-20-yn-3-one
  • (17-alpha)-17-(Acetyloxy)-19-norpregn-4-en-20-yn-3-one
  • 17-Acetyloxy(17-alpha)-19-norpregn-4-estren-17-beta-ol-acetate-3-one
  • BRN 2064104
  • EINECS 200-132-0
  • Estr-4-en-3-one, 17alpha-ethynyl-17-hydroxy-, acetate
  • Ethinyl-nortestosterone acetate
  • 17alpha-Ethinyl-19-nortestosterone-17beta-acetate
  • 17-alpha-Ethynyl-17-beta-acetoxy-19-norandrost-4-en-3-one
  • Norlutine acetate
  • 19-nor-17alpha-Pregn-4-en-20-yn-3-one, 17-acetoxy-
  • (17-alpha)-Norethindrone acetate
  • Gestakadin
  • Monogest
  • UNII-9S44LIC7OJ
  • 17-acetoxy-19-nor-17-alpha-pregn-4-en-20-yn-3-one
  • 17-acetoxy-19-nor-17alpha-pregn-4-en-20-yn-3-one
  • 17-acetyloxy(17-alpha)-19-norpregn-4-estren-17-beta-ol-acetate-3-one
  • 17-alpha-ethinyl-19-nortestosterone acetate
  • 17-alpha-ethinyl-19-nortestosterone-17-beta-acetate
  • 17-alpha-ethynyl-17-hydroxyestr-4-en-3-one acetate
  • 17-alpha-ethynyl-19-nortestosterone acetate
  • 17-hydroxy-19-nor-17-alpha-pregn-4-en-20-yn-3-one acetate
  • 17-hydroxy-19-nor-17alpha-pregn-4-en-20-yn-3-one acetate
  • 17alpha-ethinyl-19-nortestosterone 17beta-acetate
  • 17alpha-ethinyl-19-nortestosterone-17beta-acetate
  • 17alpha-ethynyl-17-hydroxyestr-4-en-3-one acetate
  • 17alpha-ethynyl-17beta-acetoxy-19-norandrost-4-en-3-one
  • 17alpha-ethynyl-19-nortestosterone acetate
  • 17beta-acetoxy-19-nor-17alpha-pregn-4-en-20-yn-3-one
  • 17beta-hydroxy-19-nor-17alpha-pregn-4-en-20-yn-3-one acetate
  • 19-norethindrone acetate
  • Norethisterone acetate

Applications:

Separation of Norethindrone acetate on Newcrom R1 HPLC column

February 16, 2018
Separation of Norethindrone acetate on Newcrom C18 HPLC column

Norethindrone acetate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Norethindrone acetate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.