Methyl oxoacetate

Methyl oxoacetate structural formula

CAS Number922-68-9
Molecular FormulaC3H4O3
Molecular Weight88.062
InChI KeyKFKXSMSQHIOMSO-UHFFFAOYSA-N
LogP-0.519
Synonyms
  • Methyl oxoacetate
  • Acetic acid, 2-oxo-, methyl ester
  • 922-68-9
  • EINECS 213-084-0
  • Glyoxylic acid, methyl ester
  • Methyl glyoxylate
  • Methyl oxoethanoate

Applications:

Separation of Methyl oxoacetate on Newcrom R1 HPLC column

February 16, 2018
Separation of Methyl oxoacetate on Newcrom C18 HPLC column

Methyl oxoacetate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Methyl oxoacetate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.