| CAS Number | 79794-75-5 |
|---|---|
| Molecular Formula | C22H23ClN2O2 |
| Molecular Weight | 382.891 |
| InChI Key | JCCNYMKQOSZNPW-UHFFFAOYSA-N |
| LogP | 5.20 |
| Synonyms |
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Applications:
Uv-Vis Spectrum of Loratadine
March 5, 2026
Access the UV-Vis Spectrum SIELC Library
If you are looking for optimized HPLC method to analyze Loratadine check our HPLC Applications library
For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The compound was diluted in acetonitrile.
HPLC Method for Analysis of Loratadine
May 3, 2016
Loratadine is a second-generation histamine H1 receptor antagonist that is used to treat symptoms of “Hay fever”, itching, runny nose, watery eyes, and sneezing, etc. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Loratadine. The method is UV compatible and can be used as a general approach for analyzing similar compounds.
Application Column
Primesep 200
The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.
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