Loratadine

Loratadine structural formula

CAS Number79794-75-5
Molecular FormulaC22H23ClN2O2
Molecular Weight382.891
InChI KeyJCCNYMKQOSZNPW-UHFFFAOYSA-N
LogP5.20
Synonyms
  • Loratadine
  • Ethyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate
  • 1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester
  • 79794-75-5
  • 1-Piperidinecarboxylic acid, 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)-, ethyl ester
  • Alavert
  • Anhissen
  • Bonalerg
  • Civeran
  • Claratyne
  • Claritin
  • Claritine
  • Clarityn
  • Clarityne
  • Cronopen
  • Flonidan
  • Fristamin
  • Histaloran
  • Klaritin
  • Lertamine
  • Loracert
  • Loradex
  • Loranox
  • Lorastine
  • Loratidine
  • Loratyne
  • Lorfast
  • Lowadina
  • Optimin
  • Polaratyne
  • Restamine
  • Sensibit
  • Sohotin
  • Velodan
  • Aerotina
  • Alerpriv
  • Allertidin
  • Bedix Loratadina
  • Biloina
  • Clarinase Reperabs
  • Clarityne Dy Repetabs
  • Clarityne-D
  • Lesidas
  • Loradif
  • Lorantis
  • Loraver
  • Loritine
  • Nularef
  • Sanelor
  • Sinhistan Dy
  • Talorat Dy
  • Children's Claritin
  • Claritin Hives Relief
  • Claritin Hives Relief Reditab
  • Claritin Reditabs
  • Loratadine Redidose
  • Loratadina
  • Loratadinum
  • UNII-7AJO3BO7QN
  • Bactimicina allergy
  • Topcare childrens allergy relief

Applications:

HPLC Method for Analysis of Loratadine

May 3, 2016

Chr_1062




Loratadine is a second-generation histamine H1 receptor antagonist that is used to treat symptoms of “Hay fever”, itching, runny nose, watery eyes, and sneezing, etc. Primesep 200, a reverse phase column, contains embedded acidic ionizable groups and can retain Loratadine. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Application Column

Primesep 200

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Loratadine
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.