Isoascorbic acid

Isoascorbic acid structural formula

CAS Number89-65-6
Molecular FormulaC6H8O6
Molecular Weight176.124
InChI KeyCIWBSHSKHKDKBQ-DUZGATOHSA-N
LogP-2.35
Synonyms
  • Isoascorbic acid
  • (5R)-5-[(1R)-1,2-Dihydroxyethyl]-3,4-dihydroxyfuran-2(5H)-one (non-preferred name)
  • 89-65-6
  • D-erythro-Hex-2-enonic acid, .gamma.-lactone
  • 5-18-05-00026
  • D-erythro-Hex-2-enonic acid, ?-lactone
  • 2,3-didehidro-D-eritro-hexono-1,4-lactona
  • 2,3-Didehydro-D- erythro-hexono-1,4-lactone
  • 2,3-Didehydro-D-erythro-hexono-1,4-lacton
  • 2,3-didehydro-D-erythro-hexono-1,4-lactone
  • Araboascorbic acid
  • Araboascorbic acid, D-
  • D-(-)-Isoascorbic acid
  • D-arabino-Ascorbic acid
  • D-araboascorbic acid
  • D-Erythorbic acid
  • D-erythro-Hexonic acid, 3-keto-, ?-lactone
  • D-Isoascorbic acid
  • Erycorbin
  • ERYTHORBIC ACID
  • Glucosaccharonic acid
  • ISOASCORBIC ACID, D-
  • ISOASCORBINSAEURE
  • Isovitamin C
  • Neo-Cebicure
  • NSC 8117
  • Saccharosonic acid
  • ?-Lactone D-erythro-hex-2-enoic acid
  • D-erythro-Ascorbic acid
  • D-ASCORBIC ACID, ISO
  • BRN 0084271
  • EINECS 201-928-0
  • Erythroascorbic acid, D-
  • FEMA No. 2410
  • FEMA Number: 2410
  • Hex-2-enonic acid gamma-lactone, D-erythro-
  • D-erythro-3-Ketohexonic acid lactone
  • 3-Keto-D-erythro-hexonic acid gamma-lactone
  • D-erythro-3-Oxohexonic acid lactone
  • 3-Oxohexonic acid lactone, D-erythro-
  • UNII-311332OII1
  • D-erythro-hex-2-enonic acid gamma-lactone
  • 74242-57-2
  • 98966-42-8

Applications:

Separation of Isoascorbic acid on Newcrom R1 HPLC column

February 16, 2018
Separation of Isoascorbic acid on Newcrom C18 HPLC column

Isoascorbic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Isoascorbic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.