Hydrocortisone acetate

Hydrocortisone acetate structural formula

CAS Number50-03-3
Molecular FormulaC23H32O6
Molecular Weight404.503
InChI KeyALEXXDVDDISNDU-KPYZGQEZSA-N
LogP2.19
Synonyms
  • Hydrocortisone acetate
  • (8xi,9xi,11beta,14xi)-11,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl acetate
  • Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-, (8xi,9xi,11beta,14xi)-
  • 50-03-3
  • Pregn-4-ene-3,20-dione, 21-(acetyloxy)-11,17-dihydroxy-, (11?)-
  • (11?)-21-(Acetyloxy)-11,17-dihydroxypregn-4-ene-3,20-dione
  • 11?,17?,21-Trihydroxypregn-4-ene-3,20-dione 21-acetate
  • 17-Hydroxycorticosterone 21-acetate
  • 17?-Hydroxycorticosterone acetate
  • 21-Acetate d'hydrocortisone
  • 21-acetato de hidrocortisona
  • 21-Acetoxy-11?,17-dihydroxypregn-4-en-3,20-dione
  • 21-Acetoxy-11?,17-dihydroxypregn-4-ene-3,20-dione
  • 21-Acetoxy-11?,17?-dihydroxypregn-4-ene-3,20-dione
  • Abbocort
  • Anusol HC
  • Bambicort
  • Berlison F
  • Biocortar
  • CaldeCort
  • Chemysone
  • Colifoam
  • Colofoam
  • Cortacream
  • Cortaid
  • Cortef acetate
  • Cortell
  • Corticaine
  • Cortifoam
  • Cortisol acetate
  • Cortisol, 21-acetate
  • Cortril acetate
  • Cortril acetate AS
  • Efcolin
  • Hycortole acetate
  • Hydrocort acetate
  • Hydrocortisat
  • Hydrocortison-21-acetat
  • hydrocortisone 21-acetate
  • Hydrocortistab
  • Hydrocortone acetate
  • Hydroxycorticosterone acetate
  • Isopto-Hydrocortisone
  • Lanacort
  • Lenirit
  • NSC 741
  • Pabracort
  • Proctocort
  • Sigmacort
  • Sintotrat
  • Velopural
  • Acetate-AS
  • Aceto-cort
  • 21-Acetoxy-11-beta,17-alpha-dihydroxypregn-4-ene-3,20-dione
  • Carmol HC
  • Collusul-HC
  • Compound F acetate
  • Corticosterone, 17-hydroxy-, 21-acetate
  • Cortril acetate-AS
  • 11-beta,17-alpha-Dihydroxy-21-acetoxypregesterone
  • EINECS 200-004-4
  • Eye-Cort
  • Hydrosone
  • 17-alpha-Hydroxycorticosterone acetate
  • 17-Hydroxycorticosterone-21-acetate
  • Hysone-A
  • Pregn-4-ene-3,20-dione, 21-(acetoxy)-11,17-dihydroxy-, (11-beta)-
  • Pregn-4-ene-3,20-dione, 11beta,17,21-trihydroxy-, 21-acetate
  • Pregn-4-ene-3,20-dione, 11-beta,17,21-trihydroxy-, 21-acetate
  • Resicort
  • Acepolcort-H
  • Alfacorton
  • Allocort
  • Berlison
  • Corti Selbe
  • Cortiderm
  • Cortidro
  • Cortiform
  • Cortimycine
  • Cortioftal
  • Crema transcutan
  • Derminovag
  • Dermosa hidrocortisona
  • Ekzemsalbe F
  • Fenitral
  • Glycocortison
  • Hipokort
  • Hycor Eye Oitment
  • Hydriocort von ct
  • Hydrison
  • Hydrocortison Streuli
  • Hydrosone-A
  • Idrocort
  • Idrocortigamma
  • Idrocortisone Acetano
  • Iracetisone
  • Latimit
  • Medithane
  • Oft Cusi Hidrocortisona
  • Ophticor
  • Pannocort
  • Posterine Corte
  • Sagittacortin
  • Sanadermil
  • Siguent Hycor
  • Soenol Hydrocortison
  • Squibb-HC
  • Supralef
  • Urecortyn
  • Dricort
  • Hemsol-HC
  • Micort-HC
  • Orabase HCA
  • UNII-3X7931PO74
  • Ala scalp

Applications:

Separation of Hydrocortisone acetate on Newcrom R1 HPLC column

February 16, 2018
Separation of Hydrocortisone acetate on Newcrom C18 HPLC column

Hydrocortisone acetate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Hydrocortisone acetate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.