HPLC MS Method for Analysis of  Alexidine on Primesep N Column

HPLC Method for Analysis of Alexidine on Primesep N Column by SIELC Technologies

Separation type: Liquid Chromatography Reversed-phase

HPLC MS Method for Analysis of Alexidine on Primesep N Column
HPLC Method for Analysis of Alexidine on Primesep N Column by SIELC Technologies

Alexidine is a chemical compound that belongs to the class of bis-biguanide antiseptics. It is known for its antimicrobial properties and is used in various products for disinfection and antiseptic purposes. Alexidine has broad-spectrum antimicrobial activity, and it is commonly used in healthcare settings for its effectiveness against bacteria, fungi, and some viruses.

Alexidine can be retained and analyzed on a Primesep N mixed-mode stationary phase column using an analytical method with a simple mobile phase of water, Acetonitrile (MeCN) , and a ammonium formate as a buffer. This analysis method can be detected using LC MS.

High Performance Liquid Chromatography (HPLC) Method for Analyses of Alexidine on Primesep N Column by SIELC Technologies

Condition

ColumnPrimesep N, 2.1 x 100 mm, 5 µm, 100 A
Mobile PhaseMeCN/H2O – 85/15%
BufferAmmonium Formate pH 3.0 – 10 mM
Flow Rate0.2 ml/min
DetectionSIM 255+, 509+

Description

Class of CompoundsBis-biguanide
Analyzing CompoundsAlexidine

Application Column

Primesep N

Column Diameter: 2.1 mm
Column Length: 100 mm
Particle Size: 5 µm
Pore Size: 100 A

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Application Analytes:
Alexidine
Application Detection:
LC MS Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.