HPLC Determination of Sodium Dodecyl Sulfate on Newcrom BH and Newcrom B Columns


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Sodium dodecyl sulfate, or sodium lauryl sulfate, is a surfactant used in cleaning and hygienic products. It has a twelve carbon hydrophobic tail attached to a polar sulfate. Dodecyl sulfate can be retained on Newcrom BH  column in under 10 minutes with an MS-compatible mobile phase.

Condition

Column Newcrom B, 4.6 x 150 mm, 5 µm, 100 A
Mobile Phase MeCN/H2O – 70/30%
Buffer AmFm pH 3.0 – 60 mM
Flow Rate 1.0 ml/min
Detection CAD (Corona) MS- compatible mobile phase

Description

Class of Compounds
Hydrophobic, Base, Ionizable, Anionic surfactant
Analyzing Compounds Sodium Dodecyl Sulfate

Application Column

Newcrom B

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A

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Application Analytes:
Sodium dodecyl sulfate

Application Detection:
CAD Detection
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