Drofenine hydrochloride

Drofenine hydrochloride structural formula

CAS Number548-66-3
Molecular FormulaC20H32ClNO2
Molecular Weight353.930
InChI KeyWIELVDXKOYPANK-UHFFFAOYSA-N
LogP4.61
Synonyms
  • Drofenine hydrochloride
  • 2-(Diethylamino)ethyl cyclohexyl(phenyl)acetate--hydrogen chloride (1/1)
  • Benzeneacetic acid, alpha-cyclohexyl-, 2-(diethylamino)ethyl ester, hydrochloride (1:1)
  • 548-66-3
  • Adiphenine H hydrochloride
  • Benzeneacetic acid, alpha-cyclohexyl-, 2-(diethylamino)ethyl ester, hydrochloride
  • Cycloadiphenine hydrochloride
  • alpha-Cyclohexylbenzeneacetic acid 2-(diethylamino)ethyl ester hydrochloride
  • Cyclohexylphenylacetyldiethylaminoethanol hydrochloride
  • Cyclovegantine
  • 2-(Diethylamino)ethyl alpha-cyclohexylbenzeneacetate
  • 2-Diethylaminoethyl(alpha-phenylcyclohexane)acetate hydrochloride
  • EINECS 208-954-1
  • Hexahydroadiphenine hydrochloride
  • NSC 42559
  • alpha-Phenylcyclohexaneacetic acid 2-(diethylamino)ethyl ester hydrochloride
  • Profenene hydrochloride
  • Trasentin H
  • Trasentine-A
  • Trasentine A
  • Drofenine HCl
  • alpha-Phenyl-cyclohexylessigsaeure-2-diaethylamino-aethylester-hydrochlorid
  • UNII-MVB31OPW05

Applications:

Separation of Drofenine hydrochloride on Newcrom R1 HPLC column

February 16, 2018
Separation of Drofenine hydrochloride on Newcrom C18 HPLC column

Drofenine hydrochloride can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Drofenine hydrochloride
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us before ordering the column as there may be a more suitable column alternative by either e-mail: support@sielc.com or by phone: 847-229-2629.