Acetophenone

Acetophenone structural formula

CAS Number98-86-2
Molecular FormulaC8H8O
Molecular Weight120.152
InChI KeyKWOLFJPFCHCOCG-UHFFFAOYSA-N
LogP1.58
Synonyms
  • Acetophenone
  • 1-Phenylethan-1-one
  • Ethanone, 1-phenyl-
  • 98-86-2
  • ethanone, 1-phenyl-
  • 1-Phenyl-1-ethanone
  • 1-Phenylethanone
  • acetofenona
  • Acetophenon
  • Acetylbenzene
  • Hypnone
  • Methyl phenyl ketone
  • NSC 7635
  • NSC 98542
  • Phenyl methyl ketone
  • Benzene, acetyl-
  • EINECS 202-708-7
  • FEMA No. 2009
  • FEMA Number 2009
  • RCRA waste number U004
  • USAF EK-496
  • UNII-RK493WHV10
  • 1-Phenyl-Ethanone
  • 1-Phenylethan-1-one
  • 1-Phenylethanone (acetophenone)
  • 1-Phenylethanone, 9CI
  • Acetofenon
  • Acetyl-Benzene
  • Acetylbenzol
  • Benzoylmethide
  • Dymex
  • FEMA 2009
  • Hypnon
  • Ketone, methyl phenyl
  • Methyl phenyl-Ketone
  • Methylphenylketone
  • Nchem.180-comp5
  • Phenyl
  • Phenylethanone
  • Phenylmethylketone
  • alpha-Acetophenone
  • benzoyl methide

Applications:

HPLC Method for Phenol – Acetone Production and Impurities

December 28, 2018

HPLC method for Phenol – Acetone production and impurities


HPLC Method for Phenol - Acetone Production and Impurities

Condition
Column Newcrom R1, 4.6×100 mm, 3 µm, 100A
Mobile Phase Gradient MeCN – 10-100%, 20 min
Buffer No
Flow Rate 1.0 ml/min
Detection UV, 207 nm

 

Description
Class of Compounds
 Neutral, Basic, Hydrophobic
Analyzing Compounds Phenol, 2-Phenyl-2-propanol, Acetophenone, Cumene Hydroperoxide, Cumene, Dicumyl Peroxide

 

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Acetophenone
Cumene
Cumene hydroperoxide
Dicumyl peroxide
Phenol
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of Acetophenone on Newcrom R1 HPLC column

February 16, 2018
Separation of Acetophenone on Newcrom C18 HPLC column

Acetophenone can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Acetophenone
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.