4-Chloro-2-methylaniline

4-Chloro-2-methylaniline structural formula

CAS Number95-69-2
Molecular FormulaC7H8ClN
Molecular Weight141.601
InChI KeyCXNVOWPRHWWCQR-UHFFFAOYSA-N
LogP2.10
Synonyms
  • 4-Chloro-2-methylaniline
  • Benzenamine, 4-chloro-2-methyl-
  • 95-69-2
  • 4-12-00-01796
  • Amarthol Fast Red TR Base
  • 2-Amino-5-chlorotoluene
  • Asymmetric meta-chloro-ortho-toluidine
  • Azoene Fast Red TR Base
  • Azoic Diazo Component 11, base
  • Brentamine Fast Red TR Base
  • BRN 0878505
  • Caswell No. 216H
  • 3-Chloro-6-aminotoluene
  • 5-Chloro-2-aminotoluene
  • 4-Chloro-6-methylaniline
  • 4-Chloro-2-methylbenzeneamine
  • p-Chloro-o-toluidine
  • Daito Red Base TR
  • Deval Red K
  • Deval Red TR
  • Diazo Fast Red TRA
  • EINECS 202-441-6
  • Fast Red 5CT Base
  • Fast Red Base TR
  • Fast Red TR
  • Fast Red TR11
  • Fast Red TR Base
  • Fast Red TRO Base
  • Kako Red TR Base
  • Kambamine Red TR
  • 2-Methyl-4-chloroaniline
  • Mitsui Red TR Base
  • NSC 4979
  • para-Chloro-ortho-toluidine
  • Red Base Ciba IX
  • Red Base IRGA IX
  • Red Base NTR
  • Red TR Base
  • Sanyo Fast Red TR Base
  • Tulabase Fast Red TR
  • UNII-95NB978426
  • 4-Chloro-o-toluidine
  • 4-Chloro-ortho-toluidine

Applications:

Separation of 4-Chloro-2-methylaniline on Newcrom R1 HPLC column

February 16, 2018
Separation of 4-Chloro-2-methylaniline on Newcrom C18 HPLC column

4-Chloro-2-methylaniline can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
4-Chloro-2-methylaniline
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.