Vitamin D3

Vitamin D3 structural formula

CAS Number67-97-0
Molecular FormulaC27H44O
Molecular Weight384.648
InChI KeyQYSXJUFSXHHAJI-YRZJJWOYSA-N
LogP8.83
Synonyms
  • Vitamin D3
  • (3S,5Z,7E)-9,10-Secocholesta-5,7,10-trien-3-ol
  • Cyclohexanol, 3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1S,3Z)-
  • 67-97-0
  • Cholecalciferol
  • 9,10-Secocholesta-5,7,10(19)-trien-3-ol, (3.beta.,5Z,7E)-
  • CHOLECALCIFEROL; (VIT. D3)
  • (3S,5Z,7E)-9,10-Secocholesta-5,7,10-trien-3-ol
  • 9,10-Secocholesta-5,7,10(19)-trien-3-ol, (3?,5Z,7E)-
  • (3,beta., 5Z, 7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
  • 9,10-Secocholesta-5,7,10(19)-trien-3?-ol
  • 9,10-Secocholestra-5,7,10(19)-trien-3-ol, (3?,5Z,7E)-
  • Arachitol
  • Calciol
  • Colecalciferol
  • Cyclohexanol, 3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]octahydro-7a-methyl-4H-inden-4-ylidene]ethylidene]-4-methylene-, (1S,3Z)-
  • D3-Vigantol
  • Delsterol
  • Deparal
  • Devaron
  • Dry Vitamin D3 100CWS/AM
  • Duphafral D3 1000
  • FeraCol
  • Granuvit D3
  • Lutavit D
  • NSC 375571
  • Oleovitamin D3
  • Quintox
  • Ricketon
  • Riken D3 Oil 20
  • Trivitan
  • Videkhol
  • Vigorsan
  • Vitinc Dan-Dee-3
  • Activated 7-dehydrocholesterol
  • Cholecalciferol, D3
  • Cholecalciferolum
  • Colecalcipherol
  • 7-Dehydrocholesterol, irradiated
  • 7-Dehydrocholestrol, activated
  • EINECS 200-673-2
  • Irradiated 7-dehydrocholesterol
  • NEO Dohyfral D3
  • Rampage
  • 9,10-Seco(5Z,7E)-5,7,10(19)-cholestatrien-3-ol
  • D3-Vicotrat
  • Vi-de-3-hydrosol
  • EPA Pesticide Chemical Code 202901
  • Colecalciferolo
  • Colecalciferolum
  • UNII-1C6V77QF41
  • (+)-vitamin D3
  • (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-1-cyclohexanol
  • (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-1-[(1R)-1,5-dimethylhexyl]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylene-cyclohexan-1-ol
  • (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidene-cyclohexan-1-ol
  • (1S,3Z)-3-[(2E)-2-[(1R,3aS,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-2,3,3a,5,6,7-hexahydro-1H-inden-4-ylidene]ethylidene]-4-methylidenecyclohexan-1-ol
  • (1S,3Z)-3-{2-[(1R,4E,7aR)-7a-methyl-1-[(2R)-6-methylheptan-2-yl]-octahydro-1H-inden-4-ylidene]ethylidene}-4-methylidenecyclohexan-1-ol
  • (3beta,5Z,7E)-9,10-secocholesta-5,7,10(19)-trien-3-ol
  • (3beta,Z,7E)-9,10-Secocholesta-5,7,10(19)-trien-3-ol
  • (5E,7E)-9,10-Secocholesta-5,7,10-trien-3-ol
  • (5Z,7E)-(3S)-9,10-secocholesta-5,7,10(19)-trien-3-ol
  • 3-beta,Z,7E-9,10-Secocholestr-5,7,10(19)-trien-3-ol
  • 9,10-Secocholesta-5,7,10(19)-trien-3-beta-ol
  • 9,10-Secocholesta-5,7,10(19)-trien-3-ol
  • 9,10-Secocholesta-5,7,10-trien-3-ol
  • CC
  • Cholecalciferol D3
  • Delsterol
  • Ebivit
  • Micro-dee
  • Provitina
  • Vi-De3
  • VidDe-3-hydrosol
  • Vigantol
  • activated 7-dehydrocholesterol
  • 8024-19-9
  • 8050-67-7

Applications:

Separation of Vitamin D3 on Newcrom R1 HPLC column

February 16, 2018
Separation of Vitamin D3 on Newcrom C18 HPLC column

Vitamin D3 can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Vitamin D3
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.