Thioglycolic acid

Thioglycolic acid structural formula

CAS Number68-11-1
Molecular FormulaC2H4O2S
Molecular Weight92.110
  • Thioglycolic acid
  • Sulfanylacetic acid
  • Acetic acid, 2-mercapto-
  • 68-11-1
  • Acetic acid, mercapto-
  • 4-03-00-00600
  • 2-Mercaptoacetic acid
  • 2-Mercaptoethanoic acid
  • 2-Thioglycolic acid
  • Acetic acid, 2-mercapto-
  • Acide mercaptoacetique
  • acido mercaptoacetico
  • Glycolic acid, 2-thio-
  • mercaptoacetic acid
  • Mercaptoessigsaure
  • NSC 1894
  • Sulfhydrylacetic acid
  • Thioglycollic acid
  • Thiovanic acid
  • UN 1940
  • ?-Mercaptoacetic acid
  • BRN 0506166
  • EINECS 200-677-4
  • Glycolic acid, thio-
  • Thioglycolate
  • Acide thioglycolique
  • Kyselina merkaptooctova
  • Kyselina thioglykolova
  • UNII-7857H94KHM
  • Mercaptoessigsaeure
  • Merkaptoessigsaeure
  • alpha-mercaptoacetic acid
  • 57755-20-1
  • 7283-42-3


Separation of Thioglycolic acid on Newcrom R1 HPLC column

May 16, 2018
Separation of Thioglycolic acid on Newcrom R1 HPLC column

Thioglycolic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Thioglycolic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: or by phone: 847-229-2629.