tert-Butyl carbamate

tert-Butyl carbamate structural formula

CAS Number4248-19-5
Molecular FormulaC5H11NO2
Molecular Weight117.149
InChI KeyLFKDJXLFVYVEFG-UHFFFAOYSA-N
LogP0.48
Synonyms
  • tert-Butyl carbamate
  • Carbamic acid, 1,1-dimethylethyl ester
  • 4248-19-5
  • EINECS 224-209-3

Applications:

Separation of tert-Butyl carbamate on Newcrom R1 HPLC column

May 16, 2018
Separation of tert-Butyl carbamate on Newcrom R1 HPLC column

tert-Butyl carbamate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
tert-Butyl carbamate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.