Sumacetamol

Sumacetamol structural formula

CAS Number69217-67-0
Molecular FormulaC15H20N2O4S
Molecular Weight324.400
InChI KeyGDRGOYFISYGSHQ-AWEZNQCLSA-N
LogP0.740
Synonyms
  • Sumacetamol
  • 4-Acetamidophenyl N-acetyl-L-methioninate
  • L-Methionine, N-acetyl-, 4-(acetylamino)phenyl ester
  • 69217-67-0
  • EINECS 273-914-2
  • Sumacetamolum
  • UNII-A0BK6FM64M

Applications:

Separation of Sumacetamol on Newcrom R1 HPLC column

May 17, 2018
Separation of Sumacetamol on Newcrom R1 HPLC column

Sumacetamol is a drug related to paracetamol. It acts as a pain reliever and a fever reducer. Sumacetamol can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particle columns are available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation of impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Sumacetamol
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.