Safrole

Safrole structural formula

CAS Number94-59-7
Molecular FormulaC10H10O2
Molecular Weight162.189
InChI KeyZMQAAUBTXCXRIC-UHFFFAOYSA-N
LogP2.82
Synonyms
  • Safrole
  • 5-(Prop-2-en-1-yl)-2H-1,3-benzodioxole
  • 1,3-Benzodioxole, 5-(2-propen-1-yl)-
  • 94-59-7
  • 5-19-01-00553
  • 1,3-Benzodioxole, 5-(2-propenyl)-
  • 1,3-Benzodioxole, 5-(2-propen-1-yl)-
  • 1-Allyl-3,4-methylenedioxybenzene
  • 3-(3,4-Methylenedioxyphenyl)prop-1-ene
  • 3, 4-Methylenedioxy-1-allylbenzene
  • 3,4-Methylenedioxy-allylbenzene
  • 4-Allyl-1,2-(methylenedioxy)benzene
  • 5-(2-Propenyl)-1,3-benzodioxole
  • 5-alil-1,3-benzodioxol
  • 5-Allyl-1,3-benzodioxol
  • 5-allyl-1,3-benzodioxole
  • 5-Allylbenzo-1,3-dioxole
  • Allylcatechol methylene ether
  • Allyldioxybenzene methylene ether
  • Allylpyrocatechol methylene ether
  • Benzene, 4-allyl-1,2-(methylenedioxy)-
  • BENZO-1,3-DIOXOLE, 5-(2-PROPENYL)-
  • m-Allylpyrocatechin methylene ether
  • NSC 11831
  • Rhyuno oil
  • Safrene
  • Safrole MF
  • Shikimole
  • Shikomol
  • 4-Allylpyrocatechol
  • 4-Allylpyrocatechol formaldehyde acetal
  • Benzene, 1,2-methylenedioxy-4-allyl-
  • 1,3-Benzodioxole, 5-allyl-
  • BRN 0136380
  • Caswell No. 729
  • EINECS 202-345-4
  • EPA Pesticide Chemical Code 097901
  • 1,2-Methylenedioxy-4-allylbenzene
  • RCRA waste number U203
  • Sassafras
  • UNII-RSB34337V9
  • 3,4-(methylenedioxy)allylbenzene
  • 4-allyl-1,2-methylenedioxybenzene
  • 4-allylpyrocatechol formaldehyde acetal
  • 5-allyl-benzo[1,3]dioxole
  • safrol
  • shikimol
  • 1406-55-9
  • 8022-92-2

Applications:

Separation of Safrole on Newcrom R1 HPLC column

February 16, 2018
Separation of Safrole on Newcrom C18 HPLC column

Safrole can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Safrole
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.