Propanoic acid, 1-methylethyl ester

Propanoic acid, 1-methylethyl ester structural formula

CAS Number637-78-5
Molecular FormulaC6H12O2
Molecular Weight116.161
  • Propanoic acid, 1-methylethyl ester
  • Propan-2-yl propanoate
  • 637-78-5
  • EINECS 211-300-8
  • FEMA No. 2959
  • Isopropyl propanoate
  • 1-Methylethyl propanoate
  • Propionic acid, isopropyl ester
  • C2H5C(O)OCH(CH3)2
  • FEMA 2959
  • Iso-propyl N-propionate
  • Iso-propyl propanoate
  • Isopropyl ester of propanoic acid
  • Isopropyl propionate [UN2409] [Flammable liquid]
  • Propionic acid isopropyl ester
  • Isopropyl propionate


Separation of Propanoic acid, 1-methylethyl ester on Newcrom R1 HPLC column

February 16, 2018
Separation of Propanoic acid, 1-methylethyl ester on Newcrom C18 HPLC column

Propanoic acid, 1-methylethyl ester can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Propanoic acid, 1-methylethyl ester
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: or by phone: 847-229-2629.