Prednisolone sodium phosphate

Prednisolone sodium phosphate structural formula

CAS Number125-02-0
Molecular FormulaC21H27Na2O8P
Molecular Weight484.392
  • Prednisolone sodium phosphate
  • Disodium (11beta)-11,17-dihydroxy-3,20-dioxopregna-1,4-dien-21-yl phosphate
  • Pregna-1,4-diene-3,20-dione, 11,17-dihydroxy-21-(phosphonooxy)-, sodium salt, (11beta)- (1:2)
  • 125-02-0
  • Codelsol
  • Disodium prednisolone 21-phosphate
  • EINECS 204-722-9
  • Hydeltrasol
  • Inflamase
  • Metreton
  • Optival
  • Phortisolone
  • Prednesol
  • Prednisolone disodium phosphate
  • Prednisolone 21-phosphate disodium
  • Predsol
  • Predsolan
  • Prozorin
  • Sodium prednisolone phosphate
  • Solucort
  • Inflamase Forte
  • Inflamase Mild
  • Predair
  • Predair Forte
  • Millipred
  • Veripred 20


Separation of Prednisolone sodium phosphate on Newcrom R1 HPLC column

February 16, 2018
Separation of Prednisolone sodium phosphate on Newcrom C18 HPLC column

Prednisolone sodium phosphate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Prednisolone sodium phosphate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: or by phone: 847-229-2629.