Polyvinylpyrrolidone (PVP)

Polyvinylpyrrolidone (PVP) is a versatile synthetic polymer widely used in life sciences and biochemical research. As a water-soluble compound, it performs multiple critical functions, including:

• Acting as a stabilizing agent
• Serving as an emulsifier and suspending agent
• Enhancing solubility of various compounds
• Functioning as a protective colloid
• Operating as a complexing agent

Its role as a protective colloid is especially important for stabilizing proteins, enzymes, and other sensitive biological molecules. This makes PVP particularly well-suited for forming stable complexes with iodine in pharmaceutical and medical formulations.

PVP can be retained and analyzed using the PVP column. The analysis utilizes an step gradient method with a simple mobile phase consisting of water, acetonitrile (MeCN), and ammonium acetate. Detection is performed using ELSD.