Pivcephalexin hydrochloride

Pivcephalexin hydrochloride structural formula

CAS Number27726-31-4
Molecular FormulaC22H28ClN3O6S
Molecular Weight497.990
InChI KeySGRIOOASEBLTKK-GNYIYVNYSA-N
LogP1.61
Synonyms
  • Pivcephalexin hydrochloride
  • [(2,2-Dimethylpropanoyl)oxy]methyl (6R,7R)-7-[2-amino(phenyl)acetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate--hydrogen chloride (1/1)
  • 5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[(2-amino-2-phenylacetyl)amino]-3-methyl-8-oxo-, (2,2-dimethyl-1-oxopropoxy)methyl ester, (6R,7R)-, hydrochloride (1:1)
  • 27726-31-4
  • EINECS 248-622-3
  • Sigmacef
  • Pivcefalexin HCl
  • Pivcefalexina

Applications:

Separation of Pivcephalexin hydrochloride on Newcrom R1 HPLC column

May 16, 2018
Separation of Pivcephalexin hydrochloride on Newcrom R1 HPLC column

Pivcephalexin hydrochloride can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Pivcephalexin hydrochloride
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us before ordering the column as there may be a more suitable column alternative by either e-mail: support@sielc.com or by phone: 847-229-2629.