Phosphonic dichloride, (chloromethyl)-

Phosphonic dichloride, (chloromethyl)- structural formula

CAS Number1983-26-2
Molecular FormulaCH2Cl3OP
Molecular Weight167.351
InChI KeyFZXSSJIKXCFPDP-UHFFFAOYSA-N
LogP1.22
Synonyms
  • Phosphonic dichloride, (chloromethyl)-
  • (Chloromethyl)phosphonic dichloride
  • Phosphonic dichloride, P-(chloromethyl)-
  • 1983-26-2
  • Chloromethane phosphoryl dichloride
  • Chloromethanephosphonic acid dichloride
  • Chloromethanephosphonyl dichloride
  • Chloromethyl dichlorophosphine oxide
  • (Chloromethyl)phosphonic acid dichloride
  • (Chloromethyl)phosphonodichloridic acid
  • Chloromethylphosphonyl dichloride
  • Dichloro(chloromethyl)phosphine oxide
  • Dichloro(chloromethyl)phosphonic acid
  • EINECS 217-848-4
  • Monochloromethyl phosphonic dichloride
  • NSC 9350
  • Phosphonic chloride, chloromethyl-
  • 112363-93-6

Applications:

Separation of Phosphonic dichloride, (chloromethyl)- on Newcrom R1 HPLC column

February 16, 2018
Separation of Phosphonic dichloride, (chloromethyl)- on Newcrom C18 HPLC column

Phosphonic dichloride, (chloromethyl)- can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Phosphonic dichloride, (chloromethyl)-
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.