Phentermine

Phentermine structural formula

CAS Number122-09-8
Molecular FormulaC10H15N
Molecular Weight149.237
InChI KeyDHHVAGZRUROJKS-UHFFFAOYSA-N
LogP1.90
Synonyms
  • Phentermine
  • 2-Methyl-1-phenylpropan-2-amine
  • Benzeneethanamine, alpha,alpha-dimethyl-
  • 122-09-8
  • Wilpo
  • Benzeneethanamine, alpha ,alpha -dimethyl-
  • (2-Amino-2-methylpropyl) benzene
  • 1,1-Dimethyl-2-phenylethylamine
  • 1-Phenyl-2-methyl-2-aminopropane
  • 1-Phenyl-2-methyl-2-propylamine
  • Duromine
  • fentermina
  • Inoamin
  • Ionamin
  • Lipopill
  • Lonamin
  • Mirapront
  • Normephentermine
  • Omnibex
  • Phenethylamine, alpha ,alpha -dimethyl-
  • Phentermin
  • Phenyl-tert-butylamine
  • alpha ,alpha -Dimethylbenzeneethanamine
  • alpha ,alpha -Dimethylphenethylamine
  • alpha ,alpha -Dimethyl-beta -phenylethylamine
  • alpha -Benzylisopropylamine
  • 2-Amino-2-methyl-1-phenylpropane
  • alpha-Benzylisopropylamine
  • BRN 0970319
  • alpha,alpha-Dimethylbenzeneethanamine
  • alpha,alpha-Dimethylphenethylamine
  • alpha,alpha-Dimethyl-beta-phenylethylamine
  • EINECS 204-522-1
  • Ethanamine, 1,1-dimethyl-2-phenyl-
  • Obermine
  • Phentrol
  • 2-Phenyl-tert-butylamine
  • Phenyl-tertiary-butylamine
  • RCRA waste number P046
  • Phenterminum
  • UNII-C045TQL4WP
  • 12674-13-4
  • 9008-94-0

Applications:

Separation of Phentermine on Newcrom R1 HPLC column

May 16, 2018
Separation of Phentermine on Newcrom R1 HPLC column

Phentermine can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Phentermine
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.