p-Hydroxycinnamic acid

p-Hydroxycinnamic acid structural formula

CAS Number7400-08-0
Molecular FormulaC9H8O3
Molecular Weight164.161
  • p-Hydroxycinnamic acid
  • 3-(4-Hydroxyphenyl)prop-2-enoic acid
  • 2-Propenoic acid, 3-(4-hydroxyphenyl)-
  • 7400-08-0
  • 4-10-00-01005
  • 2-Propenoic acid, 3-(4-hydroxyphenyl)-
  • 3-(4-Hydroxyphenyl)-2-propenoic acid
  • 3-(4-Hydroxyphenyl)acrylic acid
  • 4-Coumaric acid
  • 4'-Hydroxycinnamic acid
  • 4-hydroxycinnamic acid
  • 4-Hydroxyzimtsaure
  • Acide 4-hydroxycinnamique
  • acido 4-hidroxicinamico
  • Cinnamic acid, p-hydroxy-
  • NSC 59260
  • NSC 674321
  • p-Coumaric acid
  • p-Cumaric acid
  • p-Hydroxyphenylacrylic acid
  • ?-[4-Hydroxyphenyl]acrylic acid
  • BRN 2207383
  • EINECS 231-000-0
  • Hydroxycinnamic acid
  • beta-(4-Hydroxyphenyl)acrylic acid
  • beta-[4-hydroxyphenyl]acrylic acid
  • p-hydroxycinnamic acid
  • para-coumaric acid


Separation of p-Hydroxycinnamic acid on Newcrom R1 HPLC column

February 19, 2018
Separation of p-Hydroxycinnamic acid on Newcrom C18 HPLC column

p-Hydroxycinnamic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
p-Hydroxycinnamic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.