Nicotinic acid hydrazide

Nicotinic acid hydrazide structural formula

CAS Number553-53-7
Molecular FormulaC6H7N3O
Molecular Weight137.142
InChI KeyKFUSANSHCADHNJ-UHFFFAOYSA-N
LogP-0.663
Synonyms
  • Nicotinic acid hydrazide
  • Pyridine-3-carbohydrazide
  • 3-Pyridinecarboxylic acid, hydrazide
  • 553-53-7
  • EINECS 209-041-0
  • Hydrazine, nicotinoyl-
  • Nicotinic hydrazide
  • Nicotinoyl hydrazide
  • Nicotinoyl hydrazine
  • Nicotinylhydrazide
  • NSC 18775
  • 3-Pyridoyl hydrazine
  • (3-Pyridylcarbonyl)hydrazine
  • NSC 36088
  • UNII-AF1LLO72TM

Applications:

Separation of Nicotinic acid hydrazide on Newcrom R1 HPLC column

February 16, 2018
Separation of Nicotinic acid hydrazide on Newcrom C18 HPLC column

Nicotinic acid hydrazide can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Nicotinic acid hydrazide
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.