Methyl toluene-4-sulfonate

Methyl toluene-4-sulfonate structural formula

CAS Number80-48-8
Molecular FormulaC8H10O3S
Molecular Weight186.230
InChI KeyVUQUOGPMUUJORT-UHFFFAOYSA-N
LogP1.62
Synonyms
  • Methyl toluene-4-sulfonate
  • Methyl 4-methylbenzene-1-sulfonate
  • Benzenesulfonic acid, 4-methyl-, methyl ester
  • 80-48-8
  • Methyl 4-methylbenzenesulfonate
  • Benzenesulfonic acid, 4-methyl-, methyl ester
  • 4-11-00-00247
  • 4-Methylbenzensulfonic acid methyl ester
  • BENZENESULFONATE, 4-METHYL-, METHYL
  • Methyl p-methylbenzenesulfonate
  • Methyl p-toluenesulfonate
  • Methyl p-tosylate
  • Methyl toluenesulfonate
  • Methyl tosylate
  • Methyltoluol-4-sulfonat
  • NSC 406335
  • p-Methylbenzenesulfonic acid methyl ester
  • p-Toluenesulfonic acid, methyl ester
  • P-TOLUOLSULFONSAEURE-METHYLESTER
  • Toluene-4-sulfonate de methyle
  • TOLUENE-4-SULFONATE, METHYL
  • Toluene-4-sulfonic acid methyl ester
  • tolueno-4-sulfonato de metilo
  • BRN 0609209
  • EINECS 201-283-5
  • Methyl toluene sulfonate
  • p-Methylbenzenesulfonate methyl ester
  • Methyl-p-toluenesulfonate
  • ortho-Toluenesulfonic acid, methyl ester
  • o-Toluenesulfonic acid, methyl ester
  • 4-Toluenesulfonic acid, methyl ester
  • Methylester kyseliny p-toluensulfonove
  • p-Toluolsulfonsaeure methyl ester

Applications:

Separation of Methyl toluene-4-sulfonate on Newcrom R1 HPLC column

February 16, 2018
Separation of Methyl toluene-4-sulfonate on Newcrom C18 HPLC column

Methyl toluene-4-sulfonate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Methyl toluene-4-sulfonate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.