Isosorbide dinitrate

Isosorbide dinitrate structural formula

CAS Number87-33-2
Molecular FormulaC6H8N2O8
Molecular Weight236.137
InChI KeyMOYKHGMNXAOIAT-JGWLITMVSA-N
LogP1.31
Synonyms
  • Isosorbide dinitrate
  • 1,4:3,6-Dianhydro-2,5-di-O-nitro-D-glucitol
  • D-Glucitol, 1,4:3,6-dianhydro-, dinitrate
  • 87-33-2
  • D-Glucitol, 1,4:3,6-dianhydro-, dinitrate
  • 1,4,3,6-Sorbido-2,5-dinitric acid ester
  • 1,4:3,6-Dianhydro-D-glucitol 2,5-dinitrate
  • 1,4:3,6-Dianhydro-D-sorbitol 2,5-dinitrate
  • 1,4:3,6-Dianhydrosorbitol 2,5-dinitrate
  • Astridine
  • Cardiket
  • Carvanil
  • Carvasin
  • Cedocard
  • Claodical
  • Corosorbide
  • Corovliss
  • D-Glucitol, 1,4:3,6-dianhydro-, 2,5-dinitrate
  • Dignionitrat
  • Dilatrate
  • Dilatrate SR
  • Diniket
  • Dinitrate d'isosorbide
  • dinitrato de isosorbida
  • Dinitroisosorbide
  • Dinitrosorbide
  • Disorlon
  • D-Isosorbide dinitrate
  • Duranitrat
  • EureCor
  • Flindix
  • Frandol
  • Glentonin
  • Glucitol, 1,4:3,6-dianhydro-, dinitrate
  • Glucitol, 1,4:3,6-dianhydro-, dinitrate, D-
  • Harrical
  • Iso-Bid
  • Isocard
  • Isodinit
  • Isoket retard 40
  • Iso-Mack
  • Iso-Puren
  • Isorbid
  • Isordil
  • Isordil Tembids
  • Isosorbiddinitrat
  • Isosorbide 2,5-dinitrate
  • Isosorbide dinitrate mixture
  • Isosorbide nitrate
  • Isostenase
  • Isotrate
  • Korodil
  • Langoran
  • Laserdil
  • MIXTURE, ISOSORBIDE DINITRATE
  • Myorexon
  • Nitorol
  • Nitrofix
  • Nitrosorbid
  • Nitrosorbide
  • Nitrosorbonl Nosim
  • NSC 80038
  • Resoidan
  • Rifloc Retard
  • Rigedal
  • Risordan
  • Soni-Slo
  • Sorbangil
  • Sorbichew
  • Sorbid SA
  • Sorbide dinitrate
  • Sorbide nitrate
  • Sorbidilat
  • Sorbidnitrate
  • Sorbitol, 1,4:3,6-dianhydro-, dinitrate
  • Sorbitrate
  • Sorbonit
  • Sorbopercuten
  • Sorquad
  • UN 2907
  • Vascardin
  • Vasorbate
  • Cornilat
  • Coronex
  • Difutrat
  • EINECS 201-740-9
  • Isochron
  • Isosorbidi nitras
  • Lomilan
  • Nitrosorbon
  • Sorbide
  • Sorbide, dinitrate
  • Sorbidi nitras
  • Sorbidinitrate
  • Sorbislo
  • Sorquat
  • Tinidil
  • Vasodilat
  • Angidil
  • Isosorbide dinitrato
  • Isosorbidi dinitras
  • UNII-IA7306519N
  • Cardonit 40
  • Isoket Retard 120
  • Isomak R
  • Dianhydrosorbitol 2,5-dinitrate
  • Sorbidnitrate
  • 54650-95-2
  • 6659-58-1

Applications:

Separation of Isosorbide dinitrate on Newcrom R1 HPLC column

February 16, 2018
Separation of Isosorbide dinitrate on Newcrom C18 HPLC column

Isosorbide dinitrate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Isosorbide dinitrate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.