Isopropyl chloroformate

Isopropyl chloroformate structural formula

CAS Number108-23-6
Molecular FormulaC4H7ClO2
Molecular Weight122.551
InChI KeyIVRIRQXJSNCSPQ-UHFFFAOYSA-N
LogP1.32
Synonyms
  • Isopropyl chloroformate
  • Propan-2-yl carbonochloridate
  • Carbonochloridic acid, 1-methylethyl ester
  • 108-23-6
  • Carbonochloridic acid, 1-methylethyl ester
  • 1-Methylethyl chloroformate
  • 2-Propyl chloroformate
  • Carbonochloridic acid 1-methylethyl ester
  • CHLORAMEISENSAEURE-ISOPROPYLESTER
  • CHLOROFORMATE, ISOPROPYL
  • Chloroformiate d'isopropyle
  • Chloroformic acid isopropyl ester
  • Chloroformic acid, isopropyl ester
  • cloroformiato de isopropilo
  • Formic acid, chloro-, isopropyl ester
  • Isopropoxycarbonyl chloride
  • Isopropyl carbonochloridate
  • Isopropyl chlorocarbonate
  • Isopropylchlorformiat
  • UN 2407
  • BRN 0506416
  • Carbonochloride acid, 1-methylethyl ester
  • EINECS 203-563-2
  • Isopropyl chloromethanoate
  • Isopropylester kyseliny chlormravenci
  • UNII-8LG1G18VXR
  • 94274-22-3

Applications:

Separation of Isopropyl chloroformate on Newcrom R1 HPLC column

February 19, 2018
Separation of Isopropyl chloroformate on Newcrom C18 HPLC column

Isopropyl chloroformate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Isopropyl chloroformate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.