Hydrocortisone 21-hexanoate

Hydrocortisone 21-hexanoate structural formula

CAS Number3593-96-2
Molecular FormulaC27H40O6
Molecular Weight460.611
InChI KeyXZSVYVIYKBHVMV-FOMYWIRZSA-N
LogP4.12
Synonyms
  • Hydrocortisone 21-hexanoate
  • (11beta)-11,17-Dihydroxy-3,20-dioxopregn-4-en-21-yl hexanoate
  • Hexanoic acid, (11beta)-11,17-dihydroxy-3,20-dioxopregn-4-en-21-yl ester
  • 3593-96-2
  • Pregn-?4-?ene-?3,?20-?dione, 11,?17-?dihydroxy-?21-?[(1-?oxohexyl)?oxy]?-?, (11beta)?-
  • Cortisol, 21-hexanoate
  • Hexanoic acid, 21-ester with cortisol
  • Hydrocortisone 21-caproate
  • Hydrocortisone caproate
  • Hydrocortisone hexanoate
  • 11beta,17,21-trihydroxypregn-4-ene-3,20-dione 21-hexanoate
  • Hydrocortisone-21-yl-hexanoate
  • [2-(11,17-Dihydroxy-10,13-dimethyl-3-oxo-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-17-yl)-2-oxo-ethyl]hexanoate

Applications:

Separation of Hydrocortisone 21-hexanoate on Newcrom R1 HPLC column

May 16, 2018
Separation of Hydrocortisone 21-hexanoate on Newcrom R1 HPLC column

Hydrocortisone 21-hexanoate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Hydrocortisone 21-hexanoate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us before ordering the column as there may be a more suitable column alternative by either e-mail: support@sielc.com or by phone: 847-229-2629.