Hydrocortisone 17-butyrate

Hydrocortisone 17-butyrate structural formula

CAS Number13609-67-1
Molecular FormulaC25H36O6
Molecular Weight432.557
InChI KeyBMCQMVFGOVHVNG-TUFAYURCSA-N
LogP3.09
Synonyms
  • Hydrocortisone 17-butyrate
  • (11beta)-11,21-Dihydroxy-3,20-dioxopregn-4-en-17-yl butanoate
  • Butanoic acid, (11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-17-yl ester
  • 13609-67-1
  • Cortisol, 17-butyrate
  • EINECS 237-093-4
  • Hydrocortisone butyrate
  • Hydrocortisone-17alpha-butyrate
  • Pregn-4-ene-3,20-dione, 11,21-dihydroxy-17-(1-oxobutoxy)-, (11-beta)-
  • 11-beta,17-alpha,21-Trihydroxy-4-pregnene-3,20-dione 17-alpha-butyrate
  • Alfason
  • Hycortate
  • Lacoidon
  • Laticort
  • Locoid lipocream
  • UNII-05RMF7YPWN
  • Butanoic acid, (11beta)-11,21-dihydroxy-3,20-dioxopregn-4-en-17-yl ester
  • (11beta)-11,21-Dihydroxy-3,20-dioxopregn-4-en-17-yl butanoate
  • Pregn-?4-?ene-?3,?20-?dione, 11,?21-?dihydroxy-?17-?(1-?oxobutoxy)?-?, (11beta)?-
  • 11beta,17,21-trihydroxypregn-4-ene-3,20-dione 17-butyrate
  • Locoid
  • Plancol
  • 4-Pregnene-11beta,21-dihydroxy-17alpha-butyryloxy-3,20-dione
  • Butyric acid, 17-ester with cortisol
  • (11beta)-11,21-Dihydroxy-17-(1-oxobutoxy)pregn-4-ene-3,20-dione
  • Cortisol 17-butyrate
  • 11beta,21-dihydroxy-17alpha-butyryloxy-4-pregnene-3,20-dione
  • 17-O-butyrylcortisol
  • H-17-B
  • 82632-85-7

Applications:

Separation of Hydrocortisone 17-butyrate on Newcrom R1 HPLC column

2018-02-16
Separation of Hydrocortisone 17-butyrate on Newcrom C18 HPLC column

Hydrocortisone 17-butyrate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com" or by phone: 847-229-2629.

Application Analytes:
Hydrocortisone 17-butyrate