HPLC Method for Analysis of Tranexamic acid on Primesep 200 by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Tranexamic acid.
Tranexamic acid is a synthetic derivative of the amino acid lysine. Tranexamic acid is an antifibrinolytic agent. It works by blocking the breakdown of blood clots, which prevents bleeding. Tranexamic acid can be retained on a Primesep 200 mixed-mode column with embedded weak acidic ion-pairing groups, having great peak shape using an isocratic method of acetonitrile (ACN), water and perchloric acid (H3PO4) as a buffer. UV Detection 210nm.
| Column | Primesep 200, 4.6 x 150 mm, 5 µm, 100 A |
| Mobile Phase | MeCN/H2O – 5/95% |
| Buffer | H3PO4 – 0.1% |
| Flow Rate | 1.0 ml/min |
| Detection | UV 210 nm |
| Class of Compounds | Acid, Drug |
| Analyzing Compounds | Tranexamic acid |
Application Column
Primesep 200
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Application Analytes:
Tranexamic acidApplication Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.
