HPLC Determination of Gamma-aminobutyric Acid (GABA), Gabapentin and Pregabalin on Primesep N Column

Separation type: Liquid Chromatography Mixed-mode

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High Performance Liquid Chromatography (HPLC) Method for Analysis of GABA, Gabapentin and Pregabalin

Condition
Column	Primesep N, 4.6×150 mm, 5 µm, 100A
Mobile Phase	MeCN/H2O
Buffer	AmFm pH 3.0 – 10 mM
Flow Rate	1.0 ml/min
Detection	CAD (Corona) (MS-compatible mobile phase)

Description
Class of Compounds	Acid, Drug
Analyzing Compounds	Gamma-Aminobutyric acid (GABA), Gabapentin, Pregabalin

Application Column

Primesep N

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options

Gabapentin
Gabapentin hydrochloride
Pregabalin
gamma-Aminobutyric Acid (GABA)

SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

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HPLC Determination of Gamma-aminobutyric Acid (GABA), Gabapentin and Pregabalin on Primesep N Column

Condition

Description

Application Column

Primesep N

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